EC Number   |
Natural Substrates |
|---|
    2.3.3.10 | acetyl-CoA + acetoacetyl-CoA + H2O |
- |
| 2.3.3.10 | acetyl-CoA + H2O + acetoacetyl-CoA |
- |
| 2.3.3.10 | acetyl-CoA + acetoacetyl-CoA + H2O |
acetoacetate biosynthesis, 3-hydroxy-3-methylglutaryl-CoA pathway |
| 2.3.3.10 | acetyl-CoA + acetoacetyl-CoA + H2O |
commited step in the pathways for isoprenoid, cholesterol and ketone body production, cytosolic isoform involved in isoprenoid/cholesterol biosynthesis |
| 2.3.3.10 | acetyl-CoA + acetoacetyl-CoA + H2O |
cytosolic synthase catalyzes the second step of cholesterogenesis from acetyl-CoA |
| 2.3.3.10 | more |
enzyme activity and mRNA levels are upregulated after 3-thia fatty acid treatment |
| 2.3.3.10 | acetyl-CoA + acetoacetyl-CoA + H2O |
enzyme involved in ketone body production, control of hepatic fatty acid oxidation, potential control point for ketogenesis |
| 2.3.3.10 | acetyl-CoA + H2O + acetoacetyl-CoA |
first committed enzyme in the mevalonate pathway. The enzyme plays an important role in the biosynthesis of the sesquiterpene, which is the main constituent of essential oil in Matricaria chamomilla |
| 2.3.3.10 | acetyl-CoA + acetoacetyl-CoA + H2O |
first committed step in isoprenoid biosynthesis |
| 2.3.3.10 | more |
hydroxymethylglutaryl-CoA synthase is involved in an alternative pathway for isovaleryl-coA synthesis |
