EC Number |
Natural Substrates |
---|
2.3.1.180 | 2-methylbutyryl-CoA + malonyl-[acyl-carrier protein] |
- |
2.3.1.180 | acetyl-CoA + a malonyl-[acyl-carrier protein] |
- |
2.3.1.180 | acetyl-CoA + malonyl-[acyl-carrier protein] |
- |
2.3.1.180 | acyl-CoA + malonyl-[acyl-carrier protein] |
- |
2.3.1.180 | butyryl-CoA + malonyl-[acyl-carrier protein] |
- |
2.3.1.180 | isobutyryl-CoA + malonyl-[acyl-carrier protein] |
- |
2.3.1.180 | isovaleryl-CoA + malonyl-[acyl-carrier protein] |
- |
2.3.1.180 | more |
beta-ketoacyl-acyl carrier protein synthase III, FabH, carries out first the first condensation reaction in fatty acid biosynthesis, which determines the type of fatty acid produced in bacteria |
2.3.1.180 | acetyl-CoA + malonyl-[acyl-carrier protein] |
condensation of fatty acid synthase I-derived acyl-CoAs with malonyl-ACPs to initiates fatty acid synthase II-catalyzed fatty acid elongation, the enzyme links the two fatty acid synthase complexes |
2.3.1.180 | more |
FabH catalyzes the initial step of fatty acid biosynthesis via a type II fatty acid synthase, FabH has an important role as essential enzyme combined with unique structural features and ubiquitous occurrence |