EC Number |
Natural Substrates |
---|
2.1.3.2 | carbamoyl phosphate + L-aspartate |
- |
2.1.3.2 | carbamoylphosphate + L-aspartate |
- |
2.1.3.2 | L-aspartate + carbamoyl phosphate |
- |
2.1.3.2 | more |
ACT-DHOD gene is transcribed to ACT-DHOD mRNA, translated to the single protein, ACT-DHOD, and finally converted to mature independent DHOD and ACT |
2.1.3.2 | more |
CAD is a rate-limiting enzyme required for the formation of UDP sugar, upstream of two different metabolic pathways; the de novo biosynthesis of pyrimidine and pyrimide-based nucleotides, and the formation of UDP sugar intermediates, required for UDP-dependent glycosylation events |
2.1.3.2 | carbamoylphosphate + L-aspartate |
catalyzes the formation of carbamoyl-L-aspartate, the first compound unique to the biosynthetic pathway for pyrimidine nucleotides |
2.1.3.2 | more |
direct intermolecular interactions between the enzymes catalyzing the first three reaction steps of the de novo pyrimidine biosynthetic pathway, carbamoylphosphate synthetase II (CPSII), aspartate transcarbamoylase (ATC), and dihydroorotase (DHO), of the parasitic protist Trypanosoma cruzi, interaction analysis, overview |
2.1.3.2 | more |
link between enzyme activity and gametogenesis |
2.1.3.2 | carbamoylphosphate + L-aspartate |
second enzyme of pyrimidine synthesis |
2.1.3.2 | carbamoyl phosphate + L-aspartate |
the enzyme catalyzes the first committed step in pyrimidine biosynthesis |