EC Number   |
Natural Substrates |
|---|
   1.21.99.3 | 3,3',5'-triiodo-L-thyronine + iodide + acceptor + H+ |
- |
| 1.21.99.3 | 3,3',5'-triiodo-L-thyronine + reduced acceptor |
- |
| 1.21.99.3 | 3,3',5-triiodo-L-thyronine + AH2 |
- |
| 1.21.99.3 | 3,3',5-triiodo-L-thyronine + AH2 |
isozyme type III |
| 1.21.99.3 | 3,3',5-triiodo-L-thyronine + AH2 |
selenocysteine residue in the active site is essential for efficient inner ring deiodination |
| 1.21.99.3 | 3,3',5-triiodo-L-thyronine + AH2 |
enzyme plays a critical role in regulating and maintaining the local 3,3',5-triiodo-L-thyronine content |
| 1.21.99.3 | 3,3',5-triiodo-L-thyronine + AH2 |
no detectable activity in vivo, isozyme type III |
| 1.21.99.3 | L-thyroxine + AH2 |
- |
| 1.21.99.3 | L-thyroxine + AH2 |
5-deiodinase activity |
| 1.21.99.3 | L-thyroxine + AH2 |
in pre- and prometamorphic tadpoles, undetectable during metamorphic climax |
