EC Number   |
Natural Substrates |
|---|
   3.4.21.9 | protein C inhibitor + H2O |
- |
| 3.4.21.9 | Trypsinogen + H2O |
- |
| 3.4.21.9 | trypsinogen + H2O |
activation by by endoproteolytic cleavage |
| 3.4.21.9 | trypsinogen + H2O |
cleavage after the sequence DDDDK |
| 3.4.21.9 | trypsinogen + H2O |
cleavage sequence DDDDK-X |
| 3.4.21.9 | Trypsinogen + H2O |
enterokinase deficiency is a distinct clinical entity characterized by diarrhea, failure to thrive, hypoproteinemia, and edema. Acquired enterokinase deficiency may occur in some diffuse small bowel diseases. Steatorhea of cellac sprue may be due partly to the fact that deficiency of secretin and cholecystokinin may interfere with the action of enterokinase |
| 3.4.21.9 | more |
enterokinase light chain is a serine protease that recognizes Asp-Asp-Asp-Asp-Lys, D4K, sequence and cleaves the C-terminal peptide bond of the lysine residue |
| 3.4.21.9 | Trypsinogen + H2O |
initiates activation of pancreatic hydrolases by cleaving and activating trypsinogen |
| 3.4.21.9 | Trypsinogen + H2O |
initiation of digestive enzyme activation by converting trypsinogen into trypsin |
| 3.4.21.9 | Trypsinogen + H2O |
physiological activator of trypsinogen |
