EC Number   |
Natural Substrates |
|---|
   2.7.7.6 | ATP + RNAn |
- |
| 2.7.7.6 | CTP + RNAn |
- |
| 2.7.7.6 | GTP + RNAn |
- |
| 2.7.7.6 | nucleoside triphosphate + RNAn |
- |
| 2.7.7.6 | nucleoside triphosphate + RNAn |
a kind of transcription complex is formed during RNA polymerase catalysed synthesis of the M13 bacteriophage replication primer. The complex contains an overextended RNADNA hybrid bound in the RNA-polymerase through that is normally occupied by downstream double-stranded DNA, thus leaving the 30 end of the RNA available for interaction with DNA polymerase |
| 2.7.7.6 | nucleoside triphosphate + RNAn |
Autographa californica M nucleopolyhedrovirus transcribes genes using two DNA-directed RNA polymerases. Early genes are transcribed by the host RNA polymerase II, and late and very late genes are transcribed by a viral-encoded multisubunit RNA polymerase |
| 2.7.7.6 | more |
bacterial anti-sigma factors typically regulate sigma factor function by restricting the access of their cognate sigma-factors to the RNA polymerase RNAP core enzyme, regulation of RNAP holoenzyme, Esigma70, involving Rsd and the Rsd orthologue AlgQ, a global regulator of gene expression in Pseudomonas aeruginosa, which simultaneously interact with conserved region 2 and region 4 of sigma70 mediated by separate surfaces of Rsd, interaction with mutants of Rsd and AlgQ, mechanism, detailed overview. Rsd can strongly regulate the production of the Pseudomonas aeruginosa virulence factor pyocyanin in a manner that depends on their abilities to interact with sigma70 region 2 |
| 2.7.7.6 | nucleoside triphosphate + RNAn |
enzyme is responsible for transcription in bacteria |
| 2.7.7.6 | more |
intermittent hypoxia, a major pathological factor in the development of neural deficits associated with sleep-disordered breathing, regulates RNA polymerase II in hippocampus and prefrontal cortex. Chronic intermittent hypoxia, but not sustained hypoxia, stimulates hydroxylation of Pro1465 in large subunit of RNA polymerase II and phosphorylation of Ser5 of Rpb1, specifically in the CA1 region of the hippocampus and in the prefrontal cortex but not in other regions of the brain, requiring the von Hippel-Lindau tumor suppressor. Mice exposed to chronic IH demonstrated cognitive deficits related to dysfunction in those brain regions, overview |
| 2.7.7.6 | nucleoside triphosphate + RNAn |
mediates fast promoter-independent extension of unstable nucleic acid complexes |
