EC Number   |
Natural Substrates |
|---|
   3.1.11.1 | single-stranded oligodeoxyribonucleotide + H2O |
E. coli exonuclease I, III and V are required for stable maintenance of ColE1-related plasmids |
| 3.1.11.1 | single-stranded oligodeoxyribonucleotide + H2O |
inactivation of exonuclease I diverts most of plasmid replication activity from circular monomer production to synthesis of linear multimers |
| 3.1.11.1 | single-stranded oligodeoxyribonucleotide + H2O |
implicated in DNA repair and recombination pathways |
| 3.1.11.1 | single-stranded polydeoxyribonucleotide + H2O |
- |
| 3.1.11.1 | ssDNA + H2O |
- |
| 3.1.11.1 | ssDNA + H2O |
TTHB178 possesses 3'5'-ssExo activity that degrades ssDNAs containing deaminated and methylated bases, but not ssDNA containing oxidized bases or abasic sites. The enzyme functions in various DNA repair systems in cooperation with or independently of RecJ |
