EC Number   |
Natural Substrates |
|---|
   2.7.7.59 | UTP + [protein-GlnK] |
uridylylation of GlnK protein is essential for the cell to respond to nitrogen limitation |
| 2.7.7.59 | UTP + [protein-GlnK] |
enzyme regulates the regulatory GlnK protein |
| 2.7.7.59 | UTP + [protein-PII GlnB] |
PII-1 protein |
| 2.7.7.59 | UTP + [protein-PII GlnZ] |
PII-2 protein |
| 2.7.7.59 | UTP + [protein-PII] |
- |
| 2.7.7.59 | UTP + [protein-PII] |
the uridylylation of the PII protein is modulated by the intracellular glutamine/alpha-ketoglutarate ratio |
| 2.7.7.59 | UTP + [protein-PII] |
unlike in enterobacteria, the enzyme is not the primary nitrogen sensor, overexpression leads to derepression of nitrogen control |
| 2.7.7.59 | UTP + [protein-PII] |
enzyme is pivotal in sensing intracellular levels of fixed nitrogen |
| 2.7.7.59 | UTP + [protein-PII] |
signal transduction cascade model |
| 2.7.7.59 | UTP + [protein-PII] |
the enzyme is required for derepression of ntr-regulated promoters such as glnAp2 and pnifL, but is not involved in the nif-specific response to changes in nitrogen status mediated by the nifL products |
