EC Number   |
Natural Substrates |
|---|
   2.7.11.15 | more |
GRK2 causes enhanced catecholamine secretion by desensitizing sympatho-inhibitory alpha2-adrenergic receptors of chromaffin cells and thereby aggravating heart failure |
| 2.7.11.15 | more |
GRK2 in cardiac myocytes catalyzes phosphorylation and desensitization of different G protein-coupled receptors through specificity controlled by their carboxyl-terminal pleckstrin homology domain, overview |
| 2.7.11.15 | more |
GRK2 is important for myocardial regulation, and is up-regulated in the dysfunctional heart |
| 2.7.11.15 | more |
GRK2 substrate specificity in adult rat cardiac myocytes, overview. GRK2 completely lacks the capacity to attenuate phenylephrine-stimulated IP generation |
| 2.7.11.15 | more |
GRK3 in cardiac myocytes catalyzes phosphorylation and desensitization of different G protein-coupled receptors through specificity controlled by its carboxyl-terminal pleckstrin homology domain. GRK3 controls cardiac alpha1-adrenergic receptor responsiveness, distinct functions of GRK3 in regulation of cardiac contractility and growth, overview |
| 2.7.11.15 | more |
GRK3 substrate specificity in adult rat cardiac myocytes, overview |
| 2.7.11.15 | more |
carboxyl-terminus of GRK2 interacts with Hsp90. Reactive oxygen species (ROS)-mediated mitochrondrial localisation of GRK2 is dependent on Hsp90 binding |
| 2.7.11.15 | more |
Gprk2 interacts with the Drosophila IkB homolog Cactus |
| 2.7.11.15 | more |
GRK2 interacts with Hsp90. Reactive oxygen species (ROS)-mediated mitochrondrial localisation of GRK2 is dependent on Hsp90 binding |
| 2.7.11.15 | more |
RhoAGTP is a binding partner for enzyme GRK2 |
