EC Number |
Metals/Ions |
Reference |
---|
4.2.2.21 | Ca2+ |
- |
34086 |
4.2.2.21 | Mg2+ |
- |
34086 |
4.2.2.21 | Mn2+ |
- |
34086 |
4.2.2.21 | Ca2+ |
addition of Mg2+ or Ca2+ has a dramatically different effect on activity toward CS (glucuronic acid) and DS (iduronic acid). The specific activity for CS substrates increases only moderately (2fold) while an increase of 25fold is observed for DS |
692529 |
4.2.2.21 | Mg2+ |
addition of Mg2+ or Ca2+ has a dramatically different effect on activity toward CS (glucuronic acid) and DS (iduronic acid). The specific activity for CS substrates increases only moderately (2fold) while an increase of 25fold is observed for DS |
692529 |
4.2.2.21 | more |
for the monovalent ions tested, increasing the concentration of Na+, K+, or CS+ chloride from 0 to 0.1 M increases the activity against all substrates. Further increases in salt concentration reduces the activity dramatically, with 50% inhibition occurring at 0.15 M and a nearly complete inhibition at 0.4 M salt |
690969 |
4.2.2.21 | Ca2+ |
stimulates activity, particularly against dermatan sulfate |
690969 |
4.2.2.21 | Mg2+ |
stimulates activity, particularly against dermatan sulfate |
690969 |