EC Number   |
Metals/Ions |
Reference |
|---|
   4.2.99.18 | Zn2+ |
EndoIV contains two Fe2+ ions and one Zn2+ ion, crystallography data. The Zn2+ ion is coordinated by His182, Asp227, His229 |
713620 |
| 4.2.99.18 | Zn2+ |
His83 coordinates one of three Zn2+ ions in Apn1's active site, structure comparisons. Structure of enzyme mutant H83A Apn1-substrate DNA complex with three Zn2+ ions containing Zn2+ ions per molecule of mutant enzyme, overview. Zn2+ ions are involved in catalysis |
747170 |
| 4.2.99.18 | Zn2+ |
no effect |
648623 |
| 4.2.99.18 | Zn2+ |
required for catalysis, molecular dynamics. The active site of H83A Apn1 contains only two Zn2+ ions, with their positions being changed versus a trinuclear Zn2+ cluster of wild-type Apn1 |
747212 |
| 4.2.99.18 | Zn2+ |
stimulation half as effective as with Mg2+ |
648624 |
| 4.2.99.18 | Zn2+ |
the optimized buffer used for the exonuclease assay contains 5 mM ZnCl2 |
681675 |
