EC Number |
Localization |
GeneOntology No. |
Reference |
---|
3.6.4.7 | cytosol |
- |
GO:0005829 AmiGO QuickGO |
-, 210591, 210592, 210593, 685047, 685048, 733421, 758358 |
3.6.4.7 | cytosol |
the Pex1p/Pex6p complex exhibits a dual localization, with one fraction anchored to the peroxisomal membrane by its interaction to Pex15p and the second fraction located in the cytosol |
GO:0005829 AmiGO QuickGO |
756130 |
3.6.4.7 | cytosol |
the Pex1p/Pex6p-complex shows a dual localization in the cell as it is located in the cytosol as well as at the peroxisomal membrane |
GO:0005829 AmiGO QuickGO |
733421 |
3.6.4.7 | membrane |
- |
GO:0016020 AmiGO QuickGO |
757000 |
3.6.4.7 | more |
four Lon isoforms localize to mitochondria, plastids and peroxisomes.The peroxisome specific enzyme is Lon2, which carries a PTS1-signal |
- |
733421 |
3.6.4.7 | more |
immunohistochemic subcellular localization study |
- |
734186 |
3.6.4.7 | more |
presence of two Lon isoforms with one of them located in the peroxisomal matrix |
- |
733421 |
3.6.4.7 | more |
the AAAdomains of Pex6p seem to influence the Pex6p/Pex15p-interaction and thereby regulate the recruitment of the cytosolic AAA-complex to the peroxisomal membrane, although in opposite fashion. In particular, ATP-binding to D1 of Pex6p stimulates association of the AAA-complex with Pex15p at the peroxisomal membrane while ATP-hydrolysis at D2 seems to trigger the release of the AAA-complex from Pex15p and thus from the membrane |
- |
733421 |
3.6.4.7 | more |
the tail-anchored protein Pex15p in yeast functions as membrane anchors responsible for the recruitment of the Pex1p-Pex6p complex to the peroxisomal membrane, the N-terminal domain of Pex6p interacts with the cytosolic part of Pex15p and mediates the attachment of the Pex1p-Pex6p complex to the membrane |
- |
733421 |
3.6.4.7 | more |
the tail-anchored protein Pex26p in humans functions as membrane anchors responsible for the recruitment of the Pex1p-Pex6p complex to the peroxisomal membrane, the N-terminal domain of Pex6p interacts with the cytosolic part of Pex26p and mediates the attachment of the Pex1p-Pex6p complex to the membrane |
- |
733421 |