Leibniz Institute DSMZ
DSMZ Digital Diversity
Login
Classic view
All enzymes
Enzyme history
BRENDA support
Any feedback?
Please rate this page
(search_result.php)
😁
😐
😡
(
0
/150)
Send feedback
BRENDA support
Refine search
Search Localization
Localization:
show
10
50
100
results
Don't show organism specific information (fast!)
Search organism in taxonomic tree (slow, choose "exact" as search mode, e.g. "mammalia" for rat,human,monkey,...)
(Not possible to combine with the first option)
Refine your search
Recommended Name:
EC Number:
contains
exact
begins with
ends with
use * as joker
Commentary:
contains
exact
begins with
ends with
use * as joker
Organism
:
contains
exact
begins with
ends with
use * as joker
GeneOntology No.:
=
<
>
between min-max
use * as joker
Reference:
contains
exact
begins with
ends with
use * as joker
Show additional data
do not include text mining results
include
results
(Automatic Mining of Enzyme Data)
Search term:
Results
1
-
9
of
9
download as CSV
download all results as CSV
EC Number
Localization
Commentary
GeneOntology No.
Reference
3.4.23.15
extracellular
-
-
95751
,
95752
3.4.23.15
extracellular
active renin is significantly higher in the cell lysate than in culture medium. Inactive prorenin is similar for the intracellular and extracellular compartments. Free active renin is the predominant form found in both cell compartments. Mesangial cells in culture are able to synthesize and translate renin mRNA probably as inactive prorenin which is mostly processed to active renin inside the cells. The cells secrete both forms of the enzyme but at lower level compared with intracellular content
-
650745
3.4.23.15
extracellular
plasma
-
668473
,
668894
,
669705
3.4.23.15
extracellular
serum and synovial fluid
-
670872
3.4.23.15
intracellular
-
GO:0005622
AmiGO
QuickGO
667164
,
95752
3.4.23.15
intracellular
active renin is significantly higher in the cell lysate than in culture medium. Inactive prorenin is similar for the intracellular and extracellular compartments. Free active renin is the predominant form found in both cell compartments. Mesangial cells in culture are able to synthesize and translate renin mRNA probably as inactive prorenin which is mostly processed to active renin inside the cells. The cells secrete both forms of the enzyme but at lower level compared with intracellular content
GO:0005622
AmiGO
QuickGO
650745
3.4.23.15
membrane
renin granules
GO:0016020
AmiGO
QuickGO
95782
3.4.23.15
more
subcellular distribution
-
95782
3.4.23.15
secretory granule
renin is stored in secretory granules and is released in response to decreases in renal perfusion pressure, decreases in Cl- in the distal tubule fluid or increased sympathetic nerve stimulation via beta1-adrenoceptors
GO:0030141
AmiGO
QuickGO
711686
Results
1
-
9
of
9
download as CSV
download all results as CSV