EC Number   |
Inhibitors |
Structure |
|---|
    4.6.1.1 | (4-(6-amino-9H-purin-9-yl)cyclopent-2-en-1-yl)acetic acid |
i.e. PMC-4, type 2 enzyme, 50% inhibition at 6.998 mM, type 3 enzyme, 50% inhibition at 0.117 mM, type 5 enzyme, 50% inhibition at 0.22 mM |
   |
| 4.6.1.1 | 1,2,3,4,5,6,7,8,13,13,14,14-dodecachloro-1,4,4a,4b,5,8,8a,12b-octahydro-11-sulfo-1,4:5,8-dimethanotriphenylene-10-carboxylic acid |
the compound defines an AC inhibitor scaffold with high affinity for human soluble isozyme and less inhibitory effect on mammalian transmembrane isozymes |
|
| 4.6.1.1 | 1-(bromo(1-naphthyl)methyl)naphthalene |
- |
|
| 4.6.1.1 | 17beta-estra-1(10),2,4-triene-2,3,17-triol |
- |
|
| 4.6.1.1 | 1alpha,9alpha-dihydroxy-labd-13(E)-ene-8a,15-diol |
a derivative of each of the two stereoisomers of labd-13(E)-ene-8a,15-diol, overview |
|
| 4.6.1.1 | 1alpha-hydroxy-labd-13(E)-ene-8a,15-diol |
a derivative of each of the two stereoisomers of labd-13(E)-ene-8a,15-diol, overview |
|
| 4.6.1.1 | 2'(3')-O-(N-methylanthraniloyl)-ADP |
slight competitive inhibition |
|
| 4.6.1.1 | 2'(3')-O-(N-methylanthraniloyl)-AMP |
slight competitive inhibition |
|
| 4.6.1.1 | 2'(3')-O-(N-methylanthraniloyl)-ATP |
catalytic heterodimer VC1-IIC2 |
|
| 4.6.1.1 | 2'(3')-O-(N-methylanthraniloyl)-ATP |
competitive |
|
