EC Number   |
Inhibitors |
Structure  |
|---|
   3.4.23.5 | more |
- |
 |
| 3.4.23.5 | more |
not inhibitory: antipain, chymostatin, o-phenanthroline, phenylmethylsulfonylfluoride, iodoacetamide |
|
| 3.4.23.5 | more |
inhibitory activity of DNA is significantly dependent on Tm values of each nucleotide |
|
| 3.4.23.5 | more |
no inhibition by Ascaris pepsin inhibitor |
|
| 3.4.23.5 | more |
no inhibition by iodoacetamide and E64 (inhibitors for cysteine proteases), leupeptin, and phenylmethanesulfonyl fluoride (inhibitors for serine proteases) or EDTA and 1,10-phenanthroline (inhibitors for metalloproteases) |
|
| 3.4.23.5 | more |
when released into the plasma, cath-D is inactivated by its interaction with alpha2-macroglobulin at a neutral pH, but not at an acidic pH. DNA fragments can inhibit cath-D proteolytic activity |
|
| 3.4.23.5 | more |
cathepsin D has neither endogenous lysosomal nor cytosolic inhibitors |
|
| 3.4.23.5 | more |
not affected by 0.02 mM soybean trypsin inhibitor, 0.02 mM leupeptin, and 0.02 mM E-64 |
|
| 3.4.23.5 | more |
not inhibited by E-64, leupeptin, and phenylmethylsulfonyl fluoride |
|
| 3.4.23.5 | more |
no inhibition with phenylmethylsulfonyl fluoride, benzamidine, soybean trypsin inhibitor, TPCK, and EDTA |
|
