EC Number |
Inhibitors |
Structure |
---|
3.4.21.B40 | Aprotinin |
16% inhibition at 0.001 mM |
|
3.4.21.B40 | leupeptin |
38% inhibition at 0.001 mM |
|
3.4.21.B40 | more |
EDTA alone does not have any inhibitory effect on the enzyme activity |
|
3.4.21.B40 | phenylmethylsulfonyl fluoride |
almost complete inhibition at 10 mM |
|
3.4.21.B40 | serpin A3 |
most potent serpin inhibitor, complete inhibition at 0.001 mM |
|
3.4.21.B40 | serpin A5 |
about 40% inhibition at 0.001 mM |
|
3.4.21.B40 | serpin C1 |
about 60% inhibition at 0.001 mM |
|
3.4.21.B40 | serpin F2 |
about 35% inhibition at 0.001 mM |
|
3.4.21.B40 | Zn2+ |
reversible inhibition. 5 mM ZnCl2 almost completely abolishes the enzyme activity. EDTA (final concentration of 50 mM) completely reverses the Zn2+ inhibition |
|