EC Number   |
Inhibitors |
Structure |
|---|
    3.1.3.4 | 1,10-phenanthroline |
- |
   |
| 3.1.3.4 | 1,2-diacylglycerol |
- |
|
| 3.1.3.4 | 2,2'-dithiodipyridine |
9 mM, 90% inhibition of Mg2+-dependent enzyme, 16% inhibition of Mg2+-independent enzyme |
|
| 3.1.3.4 | 4,4'-dithiodipyridine |
9.0 mM, 96% inhibition of Mg2+-dependent enzyme, 20% inhibition of Mg2+-independent enzyme |
|
| 3.1.3.4 | 4-chlormercuriphenylsulfonic acid |
- |
|
| 3.1.3.4 | 5,5'-dithiobis(2-nitrobenzoic acid) |
0.2 mM, 80% inhibition of Mg2+-dependent enzyme, no inhibition of Mg2+-independent enzyme |
|
| 3.1.3.4 | amphiphilic amines |
- |
|
| 3.1.3.4 | ATP |
half-maximal inhibition at 0.2 mM |
|
| 3.1.3.4 | ATP |
complex inhibition of the 104-kDa enzyme form, inhibition of the 45-kDa enzyme form, inhibition by nucleotides involves the chelation of Mg2+ ions |
|
| 3.1.3.4 | ATP |
the mechanism of inhibition by ATP is complex, affecting both the Vmax and Km for phosphatidic acid, competitive to Mg2+ and involving the chelation of the cofactor |
|
