EC Number |
Inhibitors |
Structure |
---|
1.14.14.86 | more |
not inhibited by uniconazole-P |
|
1.14.14.86 | more |
among the azoles known as CYP51 inhibitors, ketoconazole, an antifungal medicine, is one of the most potent CYP51 inhibitor and forms a one-to-one complex with CYP51 as with uniconazole and CYP701B1. But ketoconazole does not bind and inhibit the purified ent-kaurene oxidase, CYP701B1; not inhibitory: ketoconazole |
|
1.14.14.86 | CO |
90% inhibition |
|
1.14.14.86 | uniconazole |
- |
|
1.14.14.86 | uniconazole |
i.e. UNI |
|
1.14.14.86 | uniconazole |
selective binding of CYP701B1 with uniconazole, is directly bound to the heme iron with its azole nitrogen |
|
1.14.14.86 | (1E,3S)-1-(4-chlorophenyl)-4,4-dimethyl-2-(1H-1,2,4-triazol-1-yl)pent-1-en-3-ol |
i.e. uniconazole |
|
1.14.14.86 | (2R,3R)-paclobutrazol |
0.0045 mM, 50% inhibition |
|
1.14.14.86 | (2R,3R)-paclobutrazol |
- |
|
1.14.14.86 | (2S,3S)-paclobutrazol |
0.00025 mM, 50% inhibition |
|