EC Number |
Inhibitors |
Structure |
---|
1.1.1.153 | more |
other unconjugated pteridines, e.g. xanthopterin, that cause slight inhibition of enzymatic reduction |
|
1.1.1.153 | more |
no inhibition by 1-epinephrine, phenylalanine, tyrosine, L-DOPA, L-tryptophan, L-5-hydroxy-tryptophan |
|
1.1.1.153 | more |
inhibition by specific antibody from rabbits |
|
1.1.1.153 | more |
Li+, Na+, Co2+, Mn2+, Ni2+ show slight inhibition at 1 mM |
|
1.1.1.153 | more |
the enzyme activity is not affected by laminar shear stress in endothelial cells, overview |
|
1.1.1.153 | more |
synergism of sulfasalazine and alpha-difluoromethylornithine (DFMO) combination treatment in neuroblastoma cells |
|
1.1.1.153 | more |
sulfonylurea- or sulfonamide-based drugs inhibit sepiapterin reduction and chemical redox cycling by sepiapterin reductase |
|
1.1.1.153 | NADPH |
above 0.1 mM |
|
1.1.1.153 | NADPH |
product inhibition, with more than 0.1 mM, with 0.05 mM sepiapterin |
|
1.1.1.153 | NADPH |
more than 0.05 mM causes substrate inhibition |
|