EC Number |
Inhibitors |
Structure |
---|
4.2.3.6 | beta-hydroxy-N-[([(Z)-[(3Z,17alpha)-17-hydroxypregn-4-en-20-yn-3-ylidene]amino]oxy)acetyl]phenylalanine |
21.1% inhibition at 0.0187 mM |
|
4.2.3.6 | diphosphate |
PPi |
|
4.2.3.6 | ethyl beta-hydroxy-N-[([(Z)-[(3Z)-17-hydroxy-20-oxopregn-4-en-3-ylidene]amino]oxy)acetyl]phenylalaninate |
25.3% inhibition at 0.0187 mM |
|
4.2.3.6 | farnesyl diphosphate analogs |
- |
|
4.2.3.6 | farnesyl diphosphate analogs |
10-fluorofarnesyl diphosphate is the most effective competitive inhibitor |
|
4.2.3.6 | methyl 1-[([(Z)-[(3Z)-20-oxopregn-4-en-3-ylidene]amino]oxy)acetyl]prolinate |
70.5% inhibition at 0.0187 mM |
|
4.2.3.6 | methyl N-[([(Z)-[(3Z)-11,17,21-trihydroxy-20-oxopregn-4-en-3-ylidene]amino]oxy)acetyl]phenylalaninate |
21.6% inhibition at 0.0187 mM |
|
4.2.3.6 | methyl N-[([(Z)-[(3Z)-11,17,21-trihydroxy-20-oxopregn-4-en-3-ylidene]amino]oxy)acetyl]tyrosinate |
22.6% inhibition at 0.0187 mM |
|
4.2.3.6 | methyl N-[([(Z)-[(3Z)-17-hydroxyandrost-4-en-3-ylidene]amino]oxy)acetyl]phenylalaninate |
53.2% inhibition at 0.0187 mM |
|
4.2.3.6 | methyl N-[([(Z)-[(3Z)-17-hydroxypregn-4-en-20-yn-3-ylidene]amino]oxy)acetyl]phenylalaninate |
66.3% inhibition at 0.0187 mM |
|