EC Number |
Inhibitors |
Structure |
---|
4.2.2.21 | more |
not inhibitory: Ni2+, Fe2+, Cu2+, Ca2+, Mg2+, Ba2+, Mn2+ |
|
4.2.2.21 | N-desulfated heparin |
50% inhibition at 0.150 mg/ml for enzyme I and 0.025 mg/ml for enzyme II |
|
4.2.2.21 | NaCl |
optimal concentration 62.5 mM for substrate chondroitin 6-sulfate, 50% inhibition at 125 mM, optimal concentration 125 mM for substrate dermatan sulfate, 50% inhibition at 250 mM |
|
4.2.2.21 | phosphate |
10 mM, 10% residual activity |
|
4.2.2.21 | Zn2+ |
- |
|
4.2.2.21 | Zn2+ |
1 mM, complete inhibition |
|