EC Number |
Inhibitors |
Structure |
---|
3.2.1.209 | more |
not inhibitory: swainsonine |
|
3.2.1.209 | N-carbobenzoxyl-leucinyl-leucinyl-leucinal |
degradation is inhibited by the proteasomal inhibitor |
|
3.2.1.209 | pepstatin A |
in the presence of mixed membrane fraction from strain ATTC 26555, the 52 kDa polypeptide is converted into a 43 kDa active product. Protease inhibitors, such as phenylmethylsulphonylfluoride, trans-epoxysuccinyl-L-leucylamido(4-guanidino)butane and 1,10-phenantroline, fail to prevent proteolysis. Pepstatin A, an aspartyl protease inhibitor, fully blocked enzyme processing |
|
3.2.1.209 | swainsonine |
inhibits hydrolysis of 4-methylumbelliferyl-alpha-D-mannopyranoside |
|
3.2.1.209 | swainsonine |
SW, inhibition of 4-methylumbelliferyl-alpha-D-mannopyranoside hydrolysis |
|
3.2.1.209 | swainsonine |
- |
|
3.2.1.209 | Zn2+ |
- |
|
3.2.1.209 | Zn2+ |
50% reduction in alpha-mannosidase activity is observed after addition of 3 mM ZnCl2 |
|