Leibniz Institute DSMZ
DSMZ Digital Diversity
Login
Classic view
All enzymes
Enzyme history
BRENDA support
Any feedback?
Please rate this page
(search_result.php)
😁
😐
😡
(
0
/150)
Send feedback
BRENDA support
Refine search
Search Inhibitors
Inhibitors:
show
10
50
100
results
Don't show organism specific information (fast!)
Search organism in taxonomic tree (slow, choose "exact" as search mode, e.g. "mammalia" for rat,human,monkey,...)
(Not possible to combine with the first option)
Refine your search
Recommended Name:
EC Number:
contains
exact
begins with
ends with
use * as joker
Commentary:
contains
exact
begins with
ends with
use * as joker
Organism
:
contains
exact
begins with
ends with
use * as joker
Reference:
contains
exact
begins with
ends with
use * as joker
Image of 2D Structure
Search for synonyms (with exact matching search term)
Search term:
Results
111
-
120
of
121
download as CSV
download all results as CSV
EC Number
Inhibitors
Commentary
Structure
2.7.7.6
Streptolydigin
-
2.7.7.6
Streptolydigin
the antibiotic binds to a Tt RNAP TEC with an open trigger loop
2.7.7.6
streptovaracin
-
2.7.7.6
streptovaricin
-
2.7.7.6
Tagetitoxin
inhibition of RNA polymerase III
2.7.7.6
Tagetitoxin
no inhibition of calf thymus RNA polymerase II
2.7.7.6
Tagetitoxin
-
2.7.7.6
Tagetitoxin
50% inhibition at 0.0001 mM. Complete inhibition at 0.01 mM
2.7.7.6
terminatin factor NsiI
N-terminally FLAG-tagged fusion protein Nsi1 expressed from Sf21 insect cells. Binding of the termination factor Nsi1 to its cognate DNA site is sufficient to terminate RNA polymerase I transcription in vitro and to induce termination in vivo. Nsi1 contains Myb-like DNA binding domains and associates in vivo near the 3' end of rRNA genes to rDNA. Binding of Nsi1 to a stretch of 11 nucleotides in the correct orientation is sufficient to pause elongating Pol I shortly upstream of the Nsi1 binding site and to release the transcripts in vitro, and the same minimal DNA element triggers Nsi1-dependent termination of pre-rRNA synthesis in vivo. Termination efficiency in the in vivo system can be enhanced by inclusion of specific DNA sequences downstream of the Nsi1 binding site
2.7.7.6
TFAM
DNA packaging by TFAM makes the DNA more resistant to unwinding
Results
111
-
120
of
121
download as CSV
download all results as CSV