EC Number   |
Inhibitors |
Structure |
|---|
    1.1.1.81 | glucose 6-phosphate |
5 mM, 49% of initial activity |
   |
| 1.1.1.81 | glucose 6-phosphate |
5 mM, 91% of initial activity |
|
| 1.1.1.81 | glycine |
- |
|
| 1.1.1.81 | glycolate |
5 mM, 15% of NADPH linked reduction |
|
| 1.1.1.81 | glyoxylate |
10 mM, 55% inhibition of NADH linked hydroxypyruvate reduction, 15% of NADPH linked reduction, 80% of NAD+ linked glycerate oxidation |
|
| 1.1.1.81 | GTP |
1 mM, 94% and 93% inhibition of liver and spinal cord enzyme respectively |
|
| 1.1.1.81 | Hg2+ |
0.1 mM, complete inhibition |
|
| 1.1.1.81 | Hydroxypyruvate |
0.5 mM, 90% of NAD+ linked glycerate oxidation |
|
| 1.1.1.81 | Hydroxypyruvate |
2 mM, 79% inhibition of enzyme activity in LaPr 88/29 mutant which lacks NADH-prefering hydroxypyruvate reductase |
|
| 1.1.1.81 | Hydroxypyruvate |
substrate inhibition at high concentrations |
|
