EC Number |
Activating Compound |
Reference |
---|
4.1.1.23 | 5,5'-dithiobis(2-nitrobenzoate) |
0.1 mM, 2.2fold stimulation |
651345 |
4.1.1.23 | 5,5'-dithiobis(2-nitrobenzoic acid) |
0.1 mM, at 70°C, 2.2fold activation |
651345 |
4.1.1.23 | 6-Azauracil |
1 mM, 1.2fold activation |
651345 |
4.1.1.23 | Uracil |
1 mM, 1.3fold stimulation |
651345 |
4.1.1.23 | N-ethylmaleimide |
10 mM, 18fold stimulation |
651345 |
4.1.1.23 | N-ethylmaleimide |
10 mM, at 70°C, 17.8fold activation |
651345 |
4.1.1.23 | phosphite dianion |
activates |
661941 |
4.1.1.23 | D-glycerol 3-phosphate |
activates the decarboxylation of 5-fluoroorotate. |
748039 |
4.1.1.23 | D-erythritol 4-phosphate |
activates the decarboxylation of 5-fluoroorotate. This activation is due to the utilization of binding energy from interactions between OMPDC and activator |
748039 |
4.1.1.23 | HPO32- |
decarboxylation of substrate analog 5'-deoxy-5-fluoroorotidine is activated. Decarboxylation of truncated substrate analog 1-(beta-D-erythrofuranosyl)-5-fluoroorotic acid is activated by exogenous phosphite dianion, but the 5-F substituent results in only a 0.8 kcal stabilization of the transition state for the phosphite-activated reaction |
727024 |