EC Number   |
Activating Compound |
Reference |
|---|
    2.1.1.5 | beta-mercaptoethanol |
using a redox-inert methyl acceptor, it is shown that BHMT requires a thiol reducing agent for activity. Short-term exposure of BHMT to reducing agent-free buffer inactivates the enzyme without causing any loss of its catalytic zinc. Activity can be completely restored by the re-addition of a thiol reducing agent |
684710 |
| 2.1.1.5 | betaine |
- |
673003 |
| 2.1.1.5 | betaine |
elevations in the liver activity |
673003 |
| 2.1.1.5 | betaine |
only slightly increased homocysteine remethylation in response to addition of betaine to diets containing 0.07 and 0.24% supplemental methionine |
676758 |
| 2.1.1.5 | betaine |
together with methionine restriction induces hepatic BHMT 4fold compared with methionine restriction alone, BHMT mRNAlevel is also increased by 3fold by betaine supplementation of methionine-replete diets |
671855 |
| 2.1.1.5 | casein |
included in liquid diets |
673003 |
| 2.1.1.5 | choline |
- |
673003 |
| 2.1.1.5 | choline |
elevations in the liver activity, whereas it has no effect in the renal enzyme |
673003 |
| 2.1.1.5 | choline |
liver BHMT activity is 1.3fold higher in rats fed the methionine deficient diet containing choline than in rats fed the methionine-adequate diet containing supplemental choline |
675565 |
| 2.1.1.5 | cystine |
- |
673003 |
