EC Number   |
Activating Compound |
Reference |
|---|
    1.12.99.6 | 3,4-dihydroxy-L-phenylalanine |
substitutes for tyrosine to stimulate in vitro HydA1 activation, improves HydA1 maturation 4fold |
706442 |
| 1.12.99.6 | demethylmenaquinone |
- |
742788 |
| 1.12.99.6 | HoxL |
the auxiliary protein HoxL participates specifically in the maturation of the large subunit of the enzyme. It is essential for H2-oxidizing activity and enzyme-driven growth on H2. HoxL acts as a specific chaperone assisting the transfer of the Fe(CN-)2CO cofactor intermediate from the Hyp machinery to the enzyme |
704518 |
| 1.12.99.6 | HoxV |
the auxiliary protein HoxL participates specifically in the maturation of the large subunit of the enzyme. It is essential for H2-oxidizing activity and enzyme-driven growth on H2. HoxV functions as a scaffold delivering the Fe(CN-)2CO moiety to the precursor of the large subunit pre-HoxG of the enzyme |
704518 |
| 1.12.99.6 | HydE |
can coordinate variable amounts of Fe and sulfide |
703727 |
| 1.12.99.6 | HydE |
from Clostridium acetobutylicum extracts, activation of HydADELTAEFG requires the presence of a preformed [4Fe-4S] cluster on HydA |
702323 |
| 1.12.99.6 | HydE |
is required to synthesize and assemble the active site utilizing Escherichia coli metabolites |
703727 |
| 1.12.99.6 | HydEF |
maturase, role in biosynthesis of the active site. HydEF and hydG, coexpressed with the structural genes hydA1 and hydA2 in Escherichia coli lead to active [FeFe]-hydrogenase |
703727 |
| 1.12.99.6 | HydF |
- |
703727 |
| 1.12.99.6 | HydF |
from Clostridium acetobutylicum extracts, activation of HydADELTAEFG requires the presence of a preformed [4Fe-4S] cluster on HydA |
702323 |
