EC Number   |
Activating Compound |
Reference  |
|---|
   7.2.2.13 | NH4+ |
stimulation, following a single saturation curve. Synergistic effects of K+ and NH4+. Km value 4.5 mM |
686200 |
| 7.2.2.13 | NH4+ |
stimulation, following a single saturation curve. Synergistic effects of K+ and NH4+. At elevated concentrations of NH4+, enzyme is fully active and K+ cannot displace NH4+ from its exclusive binding sites |
686204 |
| 7.2.2.13 | NH4+ |
stimulation, synergistic effect of NH4+ and K+. Enzyme exhibits a single K+ binding site, NH4+ binding to a second, exlcusive site |
686205 |
| 7.2.2.13 | desipramine |
inhibitor of adrenalin uptake and antidepressive action. Treatment differentially enhances the activity of Na+K+-ATPase alpha isoforms |
688762 |
| 7.2.2.13 | glyburide |
presence of 5 mM ATP, slightly stimulating up to 1 mM, inhibitory above. Presence of 0.05 mM ATP, stimulating at least up to 3 mM |
688954 |
| 7.2.2.13 | lauric acid |
presence of 5 mM ATP, inhibitory above 0.25 mM. Presence of 0.05 mM ATP, stimulating up to 0.3 mM, inhibitory above |
688954 |
| 7.2.2.13 | dexamethasone |
postnatal treatment of lamb with 0.5 mg per kg results in 21.4% increase in Na+K+-ATPase activity and a 30.4% increase in catalytic subunit alpha1 expression in the cerebral cortex. Treatment is not associated with significant changes in subunit beta1 expression. In the kidney, dexamethasone treatment is not associated with significant changes in enzyme activity, or alpha-1- or beta-1-isoform expression |
690001 |
| 7.2.2.13 | monoclonal antibody SSA 78 |
- |
696017 |
| 7.2.2.13 | polyclonal antibody pSSA 78 |
- |
696017 |
| 7.2.2.13 | Ouabain |
pretreatment of HK-2 cells with ouabain increases the Na+K+ATPase activity and inhibits the inhibitory effect of the D1 receptor on enzyme levels and activity, overview |
711774 |
