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<< < Results 11 - 14 of 14
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EC Number Activating Compound Commentary Reference
Show all pathways known for 4.1.1.23Display the word mapDisplay the reaction diagram Show all sequences 4.1.1.23phosphite dianion activates 661941
Show all pathways known for 4.1.1.23Display the word mapDisplay the reaction diagram Show all sequences 4.1.1.23phosphite dianion strong phosphite dianion activation of ScOMPDC-catalyzed decarboxylation of of 1-(beta-D-erythrofuranosyl)-5-fluoroorotate (FEO), of 5-fluoroorotate (FO) and of 1-(beta-D-erythrofuranosyl)-orotic acid. Utilization of intrinsic dianion energy 746572
Show all pathways known for 4.1.1.23Display the word mapDisplay the reaction diagram Show all sequences 4.1.1.23phosphite dianion the activation with substrate 1-(beta-D-erythrofuranosyl)-orotate is due to the utilization of binding energy from interactions between OMPDC and activator to drive a complex conformational change from inactive open OMPDC (EO) to the active closed caged complex (EC), where EC is stabilized relative to EO by interactions between dianions and the side chains of Q215, Y217, and R235 748039
Show all pathways known for 4.1.1.23Display the word mapDisplay the reaction diagram Show all sequences 4.1.1.23Uracil 1 mM, 1.3fold stimulation 651345
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