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Gene ontology
Version 2014-12-22
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Details for acetoacetate-CoA ligase activity
6.2.1.16
Gene ontology ID
GO:0030729
Definition
Catalysis of the reaction: acetoacetate + ATP + CoA = acetoacetyl-CoA + AMP + diphosphate + H(+)
Synonyms
1. acetoacetate:CoA ligase (AMP-forming)
2. acetoacetyl-CoA synthetase activity
References
1. EC 6.2.1.16
2. RHEA: 16117
3. KEGG REACTION: R01357
4. MetaCyc ACETOACETATE--COA-LIGASE-RXN
5. Reactome: R-HSA-5694494 "AACS ligates CoA-SH to ACA, forming ACA-CoA"
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
// at least 1 tissue/ enzyme/ localization link in this branch
// tissue/ enzyme/ localization link to BRENDA
Condensed Tree View
Gene ontology
molecular_function is a
catalytic activity is a
ligase activity is a
ligase activity, forming carbon-sulfur bonds is a
acid-thiol ligase activity is a
acetoacetate-CoA ligase activity is a
Tree view
Gene ontology
biological_process is a
cellular_component is a
molecular_function is a
binding is a
catalytic activity is a
catalytic activity, acting on a protein is a
catalytic activity, acting on DNA is a
catalytic activity, acting on RNA is a
cyclase activity is a
hydrolase activity is a
isomerase activity is a
ligase activity is a
beta-alanyl-dopamine synthase activity is a
delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase activity is a
ligase activity, forming carbon-carbon bonds is a
ligase activity, forming carbon-nitrogen bonds is a
ligase activity, forming carbon-oxygen bonds is a
ligase activity, forming carbon-sulfur bonds is a
acid-thiol ligase activity is a
(3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity is a
(3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity is a
2,4,4-trimethylpentanoate-CoA ligase activity is a
2,4-dichlorobenzoate-CoA ligase activity is a
2-furoate-CoA ligase activity is a
2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity is a
3-alpha,7-alpha-dihydroxy-5-beta-cholestanate-CoA ligase activity is a
3-hydroxypropionyl-CoA synthetase activity is a
3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity is a
4-chlorobenzoate-CoA ligase activity is a
4-coumarate-CoA ligase activity is a
4-hydroxybenzoate-CoA ligase activity is a
5-aminolevulinate-CoA ligase activity is a
6-carboxyhexanoate-CoA ligase activity is a
acetate-CoA ligase (ADP-forming) activity is a
acetate-CoA ligase activity is a
acetoacetate-CoA ligase activity is a
acid-CoA ligase (GDP-forming) activity is a
acyl-CoA ligase activity is a
adipate-CoA ligase activity is a
anthranilate-CoA ligase activity is a
arachidonate-CoA ligase activity is a
aryl-CoA synthetase (ADP-forming) activity is a
benzoate-CoA ligase activity is a
benzoyl acetate-CoA ligase activity is a
biotin-CoA ligase activity is a
branched-chain acyl-CoA synthetase (ADP-forming) activity is a
butyrate-CoA ligase activity is a
cholate-CoA ligase activity is a
cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity is a
cis-keto-C60-meroacyl-AMP ligase activity is a
citrate-CoA ligase activity is a
citronellyl-CoA ligase activity is a
cyclopropanecarboxylate-CoA ligase activity is a
D-alanine [D-alanyl carrier protein] ligase activity is a
decanoate-[HmqF protein] ligase activity is a
dicarboxylate-CoA ligase activity is a
fatty acid ligase activity is a
glutarate-CoA ligase activity is a
long-chain fatty acid luciferin component ligase activity is a
malate-CoA ligase activity is a
malonyl-CoA synthetase activity is a
mentha-1,3-dione-CoA ligase activity is a
o-succinylbenzoate-CoA ligase activity is a
oxalate-CoA ligase activity is a
perillic acid:CoA ligase (ADP-forming) activity is a
perillic acid:CoA ligase (AMP-forming) activity is a
phenylacetate-CoA ligase activity is a
phytanate-CoA ligase activity is a
pivalate-CoA ligase activity is a
pristanate-CoA ligase activity is a
propionate-CoA ligase activity is a
succinate-CoA ligase activity is a
thiophene-2-carboxylate-CoA ligase activity is a
trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity is a
trans-feruloyl-CoA synthase activity is a
trans-keto-C61-meroacyl-AMP ligase activity is a
trans-methoxy-C60-meroacyl-AMP ligase activity is a
[citrate (pro-3S)-lyase] ligase activity is a
CoA-ligase activity is a
fosfomycin 2-glutathione ligase activity is a
fosfomycin 2-L-cysteine ligase activity is a
ubiquitin-like modifier activating enzyme activity is a
ligase activity, forming nitrogen-metal bonds is a
ligase activity, forming phosphoric ester bonds is a
O antigen ligase activity is a
tRNA-specific 2-thiouridylase activity is a
lyase activity is a
peptidoglycan muralytic activity is a
transferase activity is a
molecular transducer activity is a
nutrient reservoir activity is a
protein tag is a
small molecule sensor activity is a
structural molecule activity is a
transcription regulator activity is a
transporter activity is a