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Literature summary extracted from

  • Viviani, F.; Vors, J.P.; Gaudry, M.; Marquet, A.
    Deoxygenation of polyphenols by ascomycetes: kinetic behavior of the NADPH-dependent naphthol dehydrogenase and inhibition by tricyclazole and its analogues (1993), Bull. Soc. Chim. Fr., 130, 395-404.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.1.1.252 1,3,8-Trihydroxynaphthalene competitive to 1,3,6,8-tetrahydroxynaphthalene Pyricularia oryzae
1.1.1.252 Tricyclazole noncompetitive with respect to 1,3,6,8-tetrahydroxynaphthalene, uncompetitive with respect to 1,3,8-trihydroxynaphthalene Pyricularia oryzae

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.1.1.252 0.0087
-
 NADPH
-
 Pyricularia oryzae
1.1.1.252 0.079
-
 1,3,6,8-Tetrahydroxynaphthalene
-
 Pyricularia oryzae
1.1.1.252 0.22
-
 Scytalone
-
 Pyricularia oryzae

Organism

EC Number Organism UniProt Comment Textmining
1.1.1.252 Pyricularia oryzae
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.1.1.252 1,3,6,8-Tetrahydroxynaphthalene + NADPH r Pyricularia oryzae Scytalone + NADP+
-
 ?
1.1.1.252 1,3,6,8-Tetrahydroxynaphthalene + NADPH spefific for NADPH Pyricularia oryzae Scytalone + NADP+
-
 ?
1.1.1.252 1,3,8-trihydroxynaphthalene + NADPH + H+ specific for NADPH Pyricularia oryzae vermelone + NADP+
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.1.1.252 5.5
-
 reduction of 1,3,6,8-tetrahydroxynaphthalene Pyricularia oryzae
1.1.1.252 7.5
-
 oxidation of scytalone Pyricularia oryzae

pH Range

EC Number pH Minimum pH Maximum Comment Organism
1.1.1.252 4.2 6.5 pH 4.2: about 40% of maximal activity, pH 6.5: about 30% of maximal activity Pyricularia oryzae
1.1.1.252 7 8 pH 7.0: about 95% of maximal activity, pH 8.0: about 80% of maximal activity Pyricularia oryzae

Cofactor

EC Number Cofactor Comment Organism Structure
1.1.1.252 NADP+
-
 Pyricularia oryzae
1.1.1.252 NADPH
-
 Pyricularia oryzae