EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.4.21.9 | antipain | - |
Sus scrofa | |
3.4.21.9 | Aprotinin | - |
Sus scrofa | |
3.4.21.9 | benzamidine | - |
Sus scrofa | |
3.4.21.9 | diisopropylphosphorofluoridate | - |
Sus scrofa | |
3.4.21.9 | trans-epoxysuccinyl-L-leucylamido-(4-guanidino)butane | - |
Sus scrofa |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.4.21.9 | 1.12 | - |
Gly-Asp-ASp-Asp-Asp-2-naphthylamide | - |
Sus scrofa | |
3.4.21.9 | 1.24 | - |
benzyloxycarbonyl-Phe-Arg-4-methylcoumarin 7-amide | - |
Sus scrofa |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
3.4.21.9 | membrane | bound | Sus scrofa | 16020 | - |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
3.4.21.9 | CoCl2 | activates | Sus scrofa | |
3.4.21.9 | HgCl2 | activates | Sus scrofa |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.21.9 | Trypsinogen + H2O | Sus scrofa | - |
? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.21.9 | Sus scrofa | - |
- |
- |
EC Number | Posttranslational Modification | Comment | Organism |
---|---|---|---|
3.4.21.9 | side-chain modification | glycosylated mainly with N-linked carbohydrate chains of the triantennary and tetraantennary complex type | Sus scrofa |
EC Number | Purification (Comment) | Organism |
---|---|---|
3.4.21.9 | - |
Sus scrofa |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.4.21.9 | duodenum | mucosa | Sus scrofa | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.21.9 | benzyloxycarbonyl-Phe-Arg-4-methylcoumaryl 7-amide + H2O | - |
Sus scrofa | ? | - |
? | |
3.4.21.9 | Gly-Asp-ASp-Asp-Asp-2-naphthylamide + H2O | - |
Sus scrofa | Gly-Asp-ASp-Asp-Asp + 2-naphthylamine | - |
? | |
3.4.21.9 | Gly-Asp-Asp-Asp-Asp-Lys-2-naphthylamide + H2O | - |
Sus scrofa | Gly-Asp-Asp-Asp-Asp-Lys + 2-naphthylamine | - |
? | |
3.4.21.9 | Lys-2-naphthylamide + H2O | - |
Sus scrofa | Lys + 2-naphthylamine | - |
? | |
3.4.21.9 | additional information | acidic residues at the P2, P3 and/or P4 position are especially favorable for maximal activity, but are not absolutely necessary | Sus scrofa | ? | - |
? | |
3.4.21.9 | tert-butoxycarbonyl-Gln-Ala-Arg-4-methylcoumarin 7-amide + H2O | weak activity | Sus scrofa | ? | - |
? | |
3.4.21.9 | tert-butoxycarbonyl-Leu-Ser-Thr-Arg-4-methylcoumaryl 7-amide + H2O | - |
Sus scrofa | ? | - |
? | |
3.4.21.9 | tert-butoxycarbonyl-Leu-Thr-Arg-4-methylcoumarin 7-amide + H2O | weak activity | Sus scrofa | ? | - |
? | |
3.4.21.9 | tert-butoxycarbonyl-Phe-Ser-Arg-4-methylcoumarin 7-amide + H2O | weak activity | Sus scrofa | ? | - |
? | |
3.4.21.9 | tert-butoxycarbonyl-Val-Leu-Lys-4-methylcoumarin 7-amide + H2O | weak activity | Sus scrofa | ? | - |
? | |
3.4.21.9 | Trypsinogen + H2O | - |
Sus scrofa | ? | - |
? |
EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.4.21.9 | 262 | - |
benzyloxycarbonyl-Phe-Arg-4-methylcoumarin 7-amide | - |
Sus scrofa | |
3.4.21.9 | 520 | - |
Gly-Asp-ASp-Asp-Asp-2-naphthylamide | - |
Sus scrofa |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
3.4.21.9 | 8 | - |
hydrolysis of Gly-Asp-Asp-Asp-Asp-Lys-2-naphthylamide | Sus scrofa |
EC Number | pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|---|
3.4.21.9 | 6.4 | 9 | 50% of maximal activity at pH 6.4 and at pH 9.0, hydrolysis of Gly-Asp-Asp-Asp-Asp-Lys-2-naphthylamide | Sus scrofa |