EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
3.1.7.1 | ATP | 0.93 mM stimulates rate of hydrolysis | Rattus norvegicus | |
3.1.7.6 | ATP | 0.93 mM, stimulates | Rattus norvegicus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.1.7.1 | 1-butanol | - |
Rattus norvegicus | |
3.1.7.1 | 3',5'-cAMP | - |
Rattus norvegicus | |
3.1.7.1 | arsenite | - |
Rattus norvegicus | |
3.1.7.1 | Co2+ | - |
Rattus norvegicus | |
3.1.7.1 | Cu2+ | - |
Rattus norvegicus | |
3.1.7.1 | dimethylallyl diphosphate | - |
Rattus norvegicus | |
3.1.7.1 | farnesoic acid | - |
Rattus norvegicus | |
3.1.7.1 | isopentenyl diphosphate | - |
Rattus norvegicus | |
3.1.7.1 | Mg2+ | loss of about 88% of activity at 10 mM | Rattus norvegicus | |
3.1.7.1 | Mn2+ | - |
Rattus norvegicus | |
3.1.7.1 | additional information | - |
Rattus norvegicus | |
3.1.7.1 | NaF | - |
Rattus norvegicus | |
3.1.7.1 | Plasma albumin | - |
Rattus norvegicus | |
3.1.7.1 | Zn2+ | - |
Rattus norvegicus | |
3.1.7.6 | (2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienoic acid | - |
Rattus norvegicus | |
3.1.7.6 | 3',5'-cAMP | - |
Rattus norvegicus | |
3.1.7.6 | arsenite | 1 mM | Rattus norvegicus | |
3.1.7.6 | isopentenyl diphosphate | competitive | Rattus norvegicus | |
3.1.7.6 | additional information | no inhibition by 1 mM p-mercuribenzoate | Rattus norvegicus | |
3.1.7.6 | Plasma albumin | - |
Rattus norvegicus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.1.7.1 | 0.7 | 1.2 | farnesol-diphosphate | - |
Rattus norvegicus | |
3.1.7.1 | 4 | 10 | dimethylallyl diphosphate | - |
Rattus norvegicus | |
3.1.7.6 | 0.7 | 1.2 | (2E,6E)-farnesyl diphosphate | pH 8.8, 37°C | Rattus norvegicus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
3.1.7.1 | microsome | - |
Rattus norvegicus | - |
- |
3.1.7.6 | microsome | - |
Rattus norvegicus | - |
- |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
3.1.7.1 | Mg2+ | 3 mM stimulates the testicular enzyme 4-10fold | Rattus norvegicus | |
3.1.7.6 | Mg2+ | slight stimulation | Rattus norvegicus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.7.1 | prenyl diphosphate + H2O | Rattus norvegicus | - |
prenol + diphosphate | - |
? | |
3.1.7.6 | (2E,6E)-farnesyl diphosphate + H2O | Rattus norvegicus | biosynthesis of acyclic sesquiterpenoids | (2E,6E)-farnesol + diphosphate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.1.7.1 | Rattus norvegicus | - |
- |
- |
3.1.7.6 | Rattus norvegicus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
3.1.7.1 | 125fold, partially purified | Rattus norvegicus |
3.1.7.6 | partial | Rattus norvegicus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.1.7.1 | liver | - |
Rattus norvegicus | - |
3.1.7.1 | testis | - |
Rattus norvegicus | - |
3.1.7.6 | testis | - |
Rattus norvegicus | - |
EC Number | Storage Stability | Organism |
---|---|---|
3.1.7.1 | frozen preperations retained activity for 1 month | Rattus norvegicus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.7.1 | farnesyl diphosphate + H2O | - |
Rattus norvegicus | farnesol + diphosphate | - |
? | |
3.1.7.1 | glucose-6-phosphate + H2O | - |
Rattus norvegicus | glucose + phosphate | - |
? | |
3.1.7.1 | isopentenyl diphosphate + H2O | - |
Rattus norvegicus | isopentenol + diphosphate | - |
? | |
3.1.7.1 | mevalonate-5-phosphate + H2O | - |
Rattus norvegicus | mevalonate + phosphate | - |
? | |
3.1.7.1 | additional information | - |
Rattus norvegicus | ? | - |
? | |
3.1.7.1 | prenyl diphosphate + H2O | - |
Rattus norvegicus | prenol + diphosphate | - |
? | |
3.1.7.6 | (2E,6E)-farnesyl diphosphate + H2O | biosynthesis of acyclic sesquiterpenoids | Rattus norvegicus | (2E,6E)-farnesol + diphosphate | - |
? | |
3.1.7.6 | (2E,6E)-farnesyl diphosphate + H2O | diphosphate is the major product, traces of phosphate. The amount of release of diphosphate is approximately equal to the amount of release of farnesol | Rattus norvegicus | (2E,6E)-farnesol + diphosphate | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.1.7.1 | prenol pyrophosphate pyrophosphohydrolase | - |
Rattus norvegicus |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
3.1.7.1 | 7.8 | - |
enzyme in crude acetone powder | Rattus norvegicus |
3.1.7.1 | 8.8 | - |
purified enzyme | Rattus norvegicus |
3.1.7.6 | 8.8 | - |
- |
Rattus norvegicus |
EC Number | pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|---|
3.1.7.6 | 8.5 | 9.1 | pH 8.5: about 40% of maximal activity, pH 9.1: about 65% of maximal activity | Rattus norvegicus |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.1.7.6 | 5.2 | - |
isopentenyl diphosphate | pH 8.8, 37°C | Rattus norvegicus |