Literature summary extracted from

Lawson, J.E.; Park, S.H.; Mattison, A.R.; Yan, J.; Reed, L.J.
Cloning, expression, and properties of the regulatory subunit of bovine pyruvate dehydrogenase phosphatase (1997), J. Biol. Chem., 272, 31625-31629.

Activating Compound

EC Number	Activating Compound	Comment	Organism	Structure
3.1.3.43	spermine	-	Bos taurus

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
3.1.3.43	expression in Escherichia coli	Bos taurus

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
3.1.3.43	mitochondrion	-	Bos taurus	5739	-

Metals/Ions

EC Number	Metals/Ions	Comment	Organism	Structure
3.1.3.43	Mg2+	-	Bos taurus

Molecular Weight [Da]

EC Number	Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
3.1.3.43	95660	-	calculated after cloning, PCR and sequencing	Bos taurus
3.1.3.43	95800	-	matrix-assisted laser desorption-ionization mass spectrometry	Bos taurus

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
3.1.3.43	[pyruvate dehydrogenase (lipoamide)]-phosphate + H2O	Bos taurus	-	?	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.1.3.43	Bos taurus	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.1.3.43	[pyruvate dehydrogenase (lipoamide)]-phosphate + H2O	-	Bos taurus	[pyruvate dehydrogenase (lipoamide)] + phosphate	-	ir
3.1.3.43	[pyruvate dehydrogenase (lipoamide)]-phosphate + H2O	-	Bos taurus	?	-	?

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Release 2023.1 (January 2023)