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Literature summary extracted from

  • Butor, C.; Higa, H.H.; Varki, A.
    Structural, immunological, and biosynthetic studies of a sialic acid-specific O-acetylesterase from rat liver (1993), J. Biol. Chem., 268, 10207-10213.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.1.53 cytosol CSE Rattus norvegicus 5829
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.1.53 28000
-
 1 * 38000 + 1 * 28000, SDS-PAGE Rattus norvegicus
3.1.1.53 38000
-
 1 * 38000 + 1 * 28000, SDS-PAGE Rattus norvegicus
3.1.1.53 52000
-
 x * 52000, glycoprotein, after treatment with endo-beta-N-acetylglycosaminidase H and peptide:N-glycosidase F Rattus norvegicus
3.1.1.53 65000
-
 x * 65000, linked to a N-oligosaccharides Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.53 Rattus norvegicus
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
3.1.1.53 side-chain modification glycoprotein, linked with N-oligosaccharides, LSE, cleaved by endo-beta-N-acetylglycosaminidase H and peptide:N-glycosidase F Rattus norvegicus

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.1.53 copurified with a 66000 Da esterase Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.53 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.53 additional information LSE can act only on O-acetyl-esters at the 9-position of sialic acids Rattus norvegicus ?
-
 ?
3.1.1.53 N-acetyl-9-O-acetylneuraminate + H2O
-
 Rattus norvegicus N-acetylneuraminate + acetate
-
 ?

Subunits

EC Number Subunits Comment Organism
3.1.1.53 ? x * 65000, linked to a N-oligosaccharides Rattus norvegicus
3.1.1.53 ? x * 52000, glycoprotein, after treatment with endo-beta-N-acetylglycosaminidase H and peptide:N-glycosidase F Rattus norvegicus
3.1.1.53 dimer 1 * 38000 + 1 * 28000, SDS-PAGE Rattus norvegicus

Synonyms

EC Number Synonyms Comment Organism
3.1.1.53 CSE
-
 Rattus norvegicus
3.1.1.53 cytosolic sialate:O-acetylesterase
-
 Rattus norvegicus
3.1.1.53 intralumenal sialate: 9-O-acetylesterase
-
 Rattus norvegicus
3.1.1.53 Lse
-
 Rattus norvegicus