Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Polokoff, M.A.; Bell, R.M.
    Characterization of liver cholic acid coenzyme A ligase activity. Evidence that separate microsomal enzymes are responsible for cholic acid and fatty acid activation (1977), J. Biol. Chem., 252, 1167-1171.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
6.2.1.7 0.01
-
 cholate
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
6.2.1.7 microsome more than 70% of the activity is associated with microsomes Rattus norvegicus
-
-

Organism

EC Number Organism UniProt Comment Textmining
6.2.1.7 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
6.2.1.7 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.2.1.7 ATP + cholate + CoA
-
 Rattus norvegicus AMP + diphosphate + choloyl-CoA
-
 ?
6.2.1.7 dATP + cholate + CoA
-
 Rattus norvegicus dAMP + diphosphate + choloyl-CoA
-
 ?

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
6.2.1.7 41
-
 half-life is about 16 min Rattus norvegicus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
6.2.1.7 8
-
-
 Rattus norvegicus