EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
3.4.21.6 | Factor V | factor Xa forms the prothrombin-converting complex with factor V, phospholipid and Ca2+ | Bos taurus | |
3.4.21.6 | Phospholipid | factor Xa forms the prothrombin-converting complex with factor V, phospholipid and Ca2+ | Bos taurus |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
3.4.21.6 | Ca2+ | factor Xa forms the prothrombin-converting complex with factor V, phospholipid and Ca2+ | Bos taurus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.21.6 | prothrombin + H2O | Bos taurus | major role is the activation of prothrombin | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.21.6 | Bos taurus | - |
- |
- |
EC Number | Posttranslational Modification | Comment | Organism |
---|---|---|---|
3.4.21.6 | proteolytic modification | factor X is the zymogen | Bos taurus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.21.6 | chymotrypsin + H2O | poor substrate | Bos taurus | ? | - |
? | |
3.4.21.6 | factor VII + H2O | cleavage of two bonds, rapid cleavage of an Arg-Ile bond and slower cleavage of an Y-Gly bond | Bos taurus | ? | - |
? | |
3.4.21.6 | factor X + H2O | cleavage of three bonds | Bos taurus | ? | - |
? | |
3.4.21.6 | prothrombin + H2O | cleaves first an Arg-Thr bond and then an Arg-Ile bond to form the two-chain enzyme | Bos taurus | thrombin + ? | - |
? | |
3.4.21.6 | prothrombin + H2O | major role is the activation of prothrombin | Bos taurus | ? | - |
? |