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Literature summary extracted from

  • Sharma, K.K.; Ortwerth, B.J.
    Purification and characterization of prolyl oligopeptidase from bovine lens (1994), Exp. Eye Res., 59, 107-116.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.21.26 diisopropylfluorophosphate
-
 Bos taurus
3.4.21.26 Elastatinal partially Bos taurus
3.4.21.26 N-ethylmaleimide
-
 Bos taurus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.21.26 72000
-
 1 * 72000, SDS-PAGE Bos taurus
3.4.21.26 72000 74000 gel filtration Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.26 Bos taurus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.21.26
-
 Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.21.26 lens
-
 Bos taurus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.4.21.26 2.87
-
-
 Bos taurus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.21.26 DRVYIHPF + H2O
-
 Bos taurus DRVYIHP + L-Phe
-
 ?
3.4.21.26 FVNEHLCGSHLVQALTLVCGQRGFFYTPLA + H2O
-
 Bos taurus FVNEHLCGSHLVQALTLVCGQRGFFYTP + LA
-
 ?
3.4.21.26 ISRPPGFSPFR + H2O
-
 Bos taurus ISRPP + GFSPFR
-
 ?
3.4.21.26 Me-O-succinyl-Ala-Ala-Val p-nitroanilide + H2O
-
 Bos taurus Me-O-succinyl-Ala-Ala + Val p-nitroanilide
-
 ?
3.4.21.26 succinyl-Gly-Pro-4-methylcoumarin 7-amide + H2O
-
 Bos taurus ?
-
 ?
3.4.21.26 tert-butyloxycarbonyl-Ala-Ala p-nitroanilide + H2O
-
 Bos taurus ?
-
 ?
3.4.21.26 tert-butyloxycarbonyl-Ala-Ala-Pro-Ala p-nitroanilide + H2O
-
 Bos taurus tert-butyloxycarbonyl-Ala-Ala-Pro + Ala + p-nitoaniline
-
 ?
3.4.21.26 VHLTPVGL + H2O
-
 Bos taurus VHLTP + VGL
-
 ?

Subunits

EC Number Subunits Comment Organism
3.4.21.26 monomer 1 * 72000, SDS-PAGE Bos taurus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.21.26 7.5
-
-
 Bos taurus