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Literature summary extracted from
- Post-proline cleaving enzyme (prolyl endopeptidase) from bovine brain (1983), J. Biochem., 94, 1179-1190.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.21.26 | 4-Chloromercuriphenylsulfonate | not | Bos taurus |  |
| 3.4.21.26 | Chloromethylketone derivatives | - |
Bos taurus | |
| 3.4.21.26 | diisopropylfluorophosphate | - |
Bos taurus | |
| 3.4.21.26 | additional information | - |
Bos taurus | |
| 3.4.21.26 | p-chloromercuribenzoate | - |
Bos taurus | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.4.21.26 | 75000 | - |
gel filtration | Bos taurus |
| 3.4.21.26 | 76000 | - |
ultracentrifugal analysis | Bos taurus |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.21.26 | Bos taurus | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.4.21.26 | - |
Bos taurus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.21.26 | brain | - |
Bos taurus | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.21.26 | benzyloxycarbonyl-Gly-Pro-2-beta-naphthylamide + H2O | - |
Bos taurus | ? | - |
? | |
| 3.4.21.26 | thyrotropin-releasing hormone + H2O | - |
Bos taurus | ? | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 3.4.21.26 | More | ? * 76000, SDS-PAGE | Bos taurus |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 3.4.21.26 | 40 | - |
- |
Bos taurus |
Temperature Stability [°C]
| EC Number | Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 3.4.21.26 | 40 | - |
pH 7.0, 15 min, 50% loss of activity | Bos taurus |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.4.21.26 | 7.2 | - |
thyrotropin releasing hormone | Bos taurus |
| 3.4.21.26 | 7.5 | - |
N-carbobenzoxy-Gly-Pro-2-beta-naphthylamide | Bos taurus |
pH Stability
| EC Number | pH Stability | pH Stability Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.4.21.26 | 5 | 9 | 30°C, 30 min | Bos taurus |
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