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Literature summary extracted from

  • Iwaya, M.; Strominger, J.L.
    Simultaneous deletion of D-alanine carboxypeptidase IB-C and penicillin-binding component IV in a mutant of Escherichia coli K12 (1977), Proc. Natl. Acad. Sci. USA, 74, 2980-2984.
    View publication on PubMedView publication on EuropePMC

Application

EC Number Application Comment Organism
3.4.17.6 medicine possible penicillin target Escherichia coli

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.17.6 additional information simultaneous mutational deletion of enzyme activity and penicillin-binding component IV Escherichia coli

Organism

EC Number Organism UniProt Comment Textmining
3.4.17.6 Escherichia coli
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mutant K12 with decreased activity
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Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.4.17.6 additional information
-
activities per g wet weight 10fold higher in wild-type than in K12 cells Escherichia coli