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Literature summary extracted from

  • Spiegelberg, B.D.; Xiong, J.P.; Smith, J.J.; Gu, R.F.; York, J.D.
    Cloning and characterization of a mammalian lithium-sensitive bisphosphate 3-nucleotidase inhibited by inositol 1,4-bisphosphate (1999), J. Biol. Chem., 274, 13619-13628.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.1.3.7 expression in Sf9 cells Homo sapiens
3.1.3.7 expression in Sf9 cells Mus musculus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.3.7 inositol 1,4-bisphosphate
-
 Homo sapiens
3.1.3.7 inositol 1,4-bisphosphate
-
 Mus musculus
3.1.3.7 Li+
-
 Mus musculus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.1.3.7 0.000475
-
 adenosine 3',5'-bisphosphate native enzyme Mus musculus
3.1.3.7 0.00052
-
 adenosine 3',5'-bisphosphate recombinant enzyme Mus musculus
3.1.3.7 0.1
-
 inositol 1,3,4-trisphosphate
-
 Mus musculus
3.1.3.7 0.113
-
 inositol 1,4-bisphosphate
-
 Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
3.1.3.7 Homo sapiens O95861 GenBank AF125042
-
3.1.3.7 Mus musculus Q9Z0S1 GenBank AF125043
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.3.7
-
 Homo sapiens
3.1.3.7
-
 Mus musculus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.3.7 adenosine 3',5'-bisphosphate + H2O
-
 Homo sapiens adenosine 5'-phosphate + phosphate
-
 ?
3.1.3.7 adenosine 3',5'-bisphosphate + H2O
-
 Mus musculus adenosine 5'-phosphate + phosphate
-
 ?
3.1.3.7 inositol 1,3,4-trisphosphate + H2O
-
 Mus musculus inositol 3,4-bisphosphate + phosphate
-
 ?
3.1.3.7 inositol 1,4-bisphosphate + H2O
-
 Mus musculus inositol 4-phosphate + phosphate
-
 ?