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Literature summary extracted from

  • Hattori, M.; Inoue, K.
    Purification and characterization of bovine brain platelet-activating factor acetylhydrolase (1993), J. Biol. Chem., 268, 18748-18753.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.1.47 diisopropylfluorophosphate intracellular enzyme form Ib from brain Bos taurus
3.1.1.47 p-bromophenacyl bromide intracellular enzyme form Ib from brain Bos taurus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.1.47 cytoplasm brain enzyme Bos taurus 5737
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.1.47 29000
-
 1 * 45000 + 1 * 30000 + 1 * 29000, intracellular enzyme form Ib from brain, SDS-PAGE Bos taurus
3.1.1.47 30000
-
 1 * 45000 + 1 * 30000 + 1 * 29000, intracellular enzyme form Ib from brain, SDS-PAGE Bos taurus
3.1.1.47 45000
-
 1 * 45000 + 1 * 30000 + 1 * 29000, intracellular enzyme form Ib from brain, SDS-PAGE Bos taurus
3.1.1.47 100000
-
 intracellular enzyme form Ib from brain, gel filtration Bos taurus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.1.47 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O Bos taurus
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.47 Bos taurus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.1.47 intracellular enzyme from brain, isoform Ib Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.47 brain
-
 Bos taurus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.1.1.47 1.45
-
 intracellular enzyme form Ib from brain Bos taurus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.47 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O i.e. PAF Bos taurus 1-O-alkyl-sn-glycero-3-phosphocholine + acetate
-
 ?
3.1.1.47 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O
-
 Bos taurus ?
-
 ?
3.1.1.47 additional information no activity against phosphatidylcholine or phosphatidylethanolamine, but hydrolysis of a phosphatidylcholine with an oxidatively fragmented acyl chain at the sn-2 position Bos taurus ?
-
 ?

Subunits

EC Number Subunits Comment Organism
3.1.1.47 trimer 1 * 45000 + 1 * 30000 + 1 * 29000, intracellular enzyme form Ib from brain, SDS-PAGE Bos taurus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.1.47 7
-
 intracellular enzyme forms from brain Bos taurus