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Literature summary extracted from

  • Hayashi, R.; Tajima, S.; Yamamoto, A.
    Purification and characterization of lipoprotein lipase from human postheparin plasma and its comparison with purified bovine milk lipoprotein lipase (1986), J. Biochem., 100, 319-331.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.1.34 apolipoprotein C-II cofactor Homo sapiens
3.1.1.34 apolipoprotein C-II cofactor Bos taurus
3.1.1.34 apolipoprotein C-II Km: 0.001 mM Homo sapiens
3.1.1.34 apolipoprotein C-II Km: 0.00015 mM Bos taurus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.1.34 NaCl 1 M NaCl, 90% inhibition Bos taurus
3.1.1.34 NaCl
-
 Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.1.1.34 1.5
-
 triolein
-
 Bos taurus
3.1.1.34 2.5
-
 triolein
-
 Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.1.34 56000
-
 x * 56000, SDS-PAGE Bos taurus
3.1.1.34 58000
-
 x * 58000, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.1.34 additional information Homo sapiens plays a key role in the metabolism of the triglyceride-rich lipoproteins, namely chylomicrons and very-low-density lipoproteins ?
-
 ?
3.1.1.34 additional information Bos taurus plays a key role in the metabolism of the triglyceride-rich lipoproteins, namely chylomicrons and very-low-density lipoproteins ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.34 Bos taurus
-
-
-
3.1.1.34 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.1.34
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.34 milk
-
 Homo sapiens
-
3.1.1.34 milk
-
 Bos taurus
-
3.1.1.34 plasma postheparin Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.1.1.34 431.6
-
-
 Homo sapiens

Storage Stability

EC Number Storage Stability Organism
3.1.1.34 0°C, 1% serum albumin, 1 h, 60% loss of activity Bos taurus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.34 additional information plays a key role in the metabolism of the triglyceride-rich lipoproteins, namely chylomicrons and very-low-density lipoproteins Homo sapiens ?
-
 ?
3.1.1.34 additional information plays a key role in the metabolism of the triglyceride-rich lipoproteins, namely chylomicrons and very-low-density lipoproteins Bos taurus ?
-
 ?
3.1.1.34 triolein + H2O
-
 Homo sapiens ?
-
 ?
3.1.1.34 triolein + H2O
-
 Bos taurus ?
-
 ?

Subunits

EC Number Subunits Comment Organism
3.1.1.34 ? x * 56000, SDS-PAGE Bos taurus
3.1.1.34 ? x * 58000, SDS-PAGE Homo sapiens

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
3.1.1.34 37
-
 10 min, absence of apop C-II, 15% loss of activity Bos taurus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.1.34 8.7
-
-
 Homo sapiens
3.1.1.34 8.7
-
-
 Bos taurus

pH Range

EC Number pH Minimum pH Maximum Comment Organism
3.1.1.34 7.2 8.9 pH 7.2: about 45% of maximal activity, pH 8.9: about 95% of maximal activity Bos taurus