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Literature summary extracted from

  • Lookene, A.; Groot, N.B.; Kastelein, J.J.P.; Olivecrona, G.; Bruin, T.
    Mutation of tryptophan residues in lipoprotein lipase. Effects on stability, immunoreactivity, and catalytic properties (1997), J. Biol. Chem., 272, 766-772.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.1.1.34
-
 Bos taurus

Protein Variants

EC Number Protein Variants Comment Organism
3.1.1.34 W114A completely inactive lipase Bos taurus
3.1.1.34 W390A decreased activity with monoclonal antibody 5D2, decreased activity against a synthetic emulsion of long-chain triacylglycerols and in particular against rat lymph chylomicrons Bos taurus
3.1.1.34 W55A completely inactive lipase Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.34 Bos taurus
-
 wild-type enzyme and mutant enzymes W382A, W390A, W393A, W394A, W393A/W394A and W114A
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.34 milk
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.34 chylomicrons + H2O wild-type enzyme and mutant enzymes Bos taurus ?
-
 ?
3.1.1.34 tributyrin + H2O wild-type enzyme and mutant enzymes Bos taurus ?
-
 ?