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Literature summary extracted from

  • Yuki, S.; Uemura, A.; Hakozaki, M.; Yano, A.; Abe, M.; Misawa, Y.; Baba, N.; Yamada, H.
    Identification of a novel enzyme from E. pacifica that acts as an eicosapentaenoic 8R-LOX and docosahexaenoic 10R-LOX (2020), Sci. Rep., 10, 20592 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.13.11.40 expression in Sf9 cells using a baculovirus expression system Euphausia pacifica

Organism

EC Number Organism UniProt Comment Textmining
1.13.11.40 Euphausia pacifica A0A7G1H6X8 isoform Lox-1
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.13.11.40 17S-hydroxy-docosa-4Z,7Z,10Z,13Z,15E,19Z-hexaenoic acid + O2
-
 Euphausia pacifica 10R,17S-dihydroxy-docosa-4Z,7Z,11E,13Z,15E,19Z-hexaenoic acid
-
 ?
1.13.11.40 arachidonic acid + O2
-
 Euphausia pacifica 8R-hydroxy-eicosatetraenoic acid
-
 ?
1.13.11.40 docosahexaenoic acid + O2
-
 Euphausia pacifica 10R-hydroxy-docosahexaenoic acid
-
 ?
1.13.11.40 eicosapentaenoic acid + O2
-
 Euphausia pacifica 8R-hydroxy-eicosapentaenoic acid
-
 ?
1.13.11.40 additional information LOX1 has higher activity for eicosapentaenoic acid than arachidonic acid and docosahexaenoic acid Euphausia pacifica ?
-
-
1.13.11.40 stearidonic acid + O2
-
 Euphausia pacifica 6-hydroxystearidonic acid
-
 ?

Subunits

EC Number Subunits Comment Organism
1.13.11.40 ? x * 80000, SDS-PAGE Euphausia pacifica

Synonyms

EC Number Synonyms Comment Organism
1.13.11.40 eicosapentaenoic 8R-lipoxygenase
-
 Euphausia pacifica
1.13.11.40 LOX-1
-
 Euphausia pacifica

Temperature Range [°C]

EC Number Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
1.13.11.40 4 40
-
 Euphausia pacifica

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.13.11.40 7
-
-
 Euphausia pacifica