Literature summary extracted from

Larue, C.T.; Ream, J.E.; Zhou, X.; Moshiri, F.; Howe, A.; Goley, M.; Sparks, O.C.; Voss, S.T.; Hall, E.; Ellis, C.; Weihe, J.; Qi, Q.; Ribeiro, D.; Wei, X.; Guo, S.; Evdokimov, A.G.; Varagona, M.J.; Roberts, J.K.
Microbial HemG-type protoporphyrinogen IX oxidase enzymes for biotechnology applications in plant herbicide tolerance traits (2020), Pest Manag. Sci., 76, 1031-1038 .

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
1.3.3.4	expressed in Escherichia coli HemG-knock-out strain as well as maize, soybean cotton, and canola	Escherichia coli

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
1.3.3.4	acifluorfen	-	Escherichia coli
1.3.3.4	ethyl [(3-(2-chloro-4-fluoro-5-[3-methyl-2,6-dioxo-4-(trifluoromethyl)-3,6-dihydropyrimidin-1(2H)-yl]phenoxy)pyridin-2-yl)oxy]acetate	i.e. S3100	Escherichia coli
1.3.3.4	flumioxazin	-	Escherichia coli
1.3.3.4	fomesafen	-	Escherichia coli
1.3.3.4	lactofen	-	Escherichia coli

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
1.3.3.4	protoporphyrinogen IX + 3 O2	Escherichia coli	-	protoporphyrin IX + 3 H2O2	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.3.3.4	Escherichia coli	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.3.3.4	protoporphyrinogen IX + 3 O2	-	Escherichia coli	protoporphyrin IX + 3 H2O2	-	?

Synonyms

EC Number	Synonyms	Comment	Organism
1.3.3.4	HemG	-	Escherichia coli
1.3.3.4	H_N10	isoform	Escherichia coli
1.3.3.4	H_N40	isoform	Escherichia coli
1.3.3.4	H_N90	isoform	Escherichia coli
1.3.3.4	PPO	-	Escherichia coli
1.3.3.4	protoporphyrinogen IX oxidase	-	Escherichia coli

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
1.3.3.4	FAD	-	Escherichia coli

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Release 2023.1 (January 2023)