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Literature summary extracted from

  • Youn, J.H.; Kim, T.W.; Joo, S.H.; Son, S.H.; Roh, J.; Kim, S.; Kim, T.W.; Kim, S.K.
    Function and molecular regulation of DWARF1 as a C-24 reductase in brassinosteroid biosynthesis in Arabidopsis (2018), J. Exp. Bot., 69, 1873-1886 .
    View publication on PubMedView publication on EuropePMC

Organism

EC Number Organism UniProt Comment Textmining
1.3.1.72 Arabidopsis thaliana
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.3.1.72 24-methylenecholesterol + NADPH + H+
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 Arabidopsis thaliana campesterol + NADP+
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 ?
1.3.1.72 additional information the enzyme has enzyme activity not only for a sterol C-24 reductase, but also for a brassinosteroid C-24 reductase that catalyzes C-24 reduction of 6-deoxodolichosterone to 6-deoxocastasterone and of dolichosterone to castasterone in Arabidopsis thaliana Arabidopsis thaliana ?
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Synonyms

EC Number Synonyms Comment Organism
1.3.1.72 DWARF1
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 Arabidopsis thaliana
1.3.1.72 DWF1
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 Arabidopsis thaliana
1.3.1.72 sterol C-24 reductase
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 Arabidopsis thaliana

Expression

EC Number Organism Comment Expression
1.3.1.72 Arabidopsis thaliana enzyme expression is down-regulated by application of castasterone and brassinolide down

General Information

EC Number General Information Comment Organism
1.3.1.72 metabolism biosynthesis of 24-methylene brassinosteroid is an alternative route for generating castasterone, which is mediated and regulated by the enzyme in Arabidopsis thaliana Arabidopsis thaliana
1.3.1.72 physiological function the enzyme functions in biosynthesis of active brassinosteroids in Arabidopsis thaliana. Enzyme overexpression enhances growth and development in Arabidopsis Arabidopsis thaliana