EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.4.3.5 | 1-(propan-2-yl)-6-[2-[4-(propan-2-yl)phenoxy]ethoxy]-1,3-dihydro-2H-benzimidazol-2-one | - |
Drosophila melanogaster | |
1.4.3.5 | 1-ethyl-6-[2-(3-fluorophenoxy)ethoxy]-1,3-dihydro-2H-benzimidazol-2-one | - |
Drosophila melanogaster | |
1.4.3.5 | 1-ethyl-6-[2-[4-(propan-2-yl)phenoxy]ethoxy]-1,3-dihydro-2H-benzimidazol-2-one | - |
Drosophila melanogaster | |
1.4.3.5 | 1-ethyl-6-[[4-(trifluoromethyl)phenyl]methoxy]-1,3-dihydro-2H-benzimidazol-2-one | - |
Drosophila melanogaster | |
1.4.3.5 | 1-methyl-6-(3-phenylpropoxy)-1,3-dihydro-2H-benzimidazol-2-one | - |
Drosophila melanogaster | |
1.4.3.5 | 5-[(3,4-dichlorophenyl)methoxy]-1,3-dihydro-2H-indol-2-one | - |
Drosophila melanogaster | |
1.4.3.5 | 5-[(3,4-dichlorophenyl)methoxy]-1H-indole-2,3-dione | - |
Drosophila melanogaster | |
1.4.3.5 | 5-[(3,4-dichlorophenyl)methoxy]-3,3-dimethyl-1,3-dihydro-2H-indol-2-one | - |
Drosophila melanogaster | |
1.4.3.5 | 5-[(3-chlorophenyl)methoxy]-1H-indole-2,3-dione | - |
Drosophila melanogaster | |
1.4.3.5 | 5-[(3-chlorophenyl)methoxy]-3,3-dimethyl-1,3-dihydro-2H-indol-2-one | - |
Drosophila melanogaster | |
1.4.3.5 | 5-[(3-fluorophenyl)methoxy]-3-(propan-2-yl)-1,3-dihydro-2H-indol-2-one | - |
Drosophila melanogaster | |
1.4.3.5 | 5-[(4-fluorophenyl)methoxy]-1,3-dihydro-2H-indol-2-one | - |
Drosophila melanogaster | |
1.4.3.5 | 5-[(4-fluorophenyl)methoxy]-1H-indole-2,3-dione | - |
Drosophila melanogaster | |
1.4.3.5 | 5-[2-(4-fluorophenyl)ethoxy]-1,3-dihydro-2H-indol-2-one | - |
Drosophila melanogaster | |
1.4.3.5 | 5-[2-(4-fluorophenyl)ethoxy]-1H-indole-2,3-dione | - |
Drosophila melanogaster | |
1.4.3.5 | 6-[(3,4-dichlorophenyl)methoxy]-1-methyl-1,3-dihydro-2H-benzimidazol-2-one | - |
Drosophila melanogaster | |
1.4.3.5 | 6-[(3-chlorophenyl)methoxy]-1-methyl-1,3-dihydro-2H-benzimidazol-2-one | - |
Drosophila melanogaster | |
1.4.3.5 | 6-[(4-chlorophenyl)methoxy]-1-methyl-1,3-dihydro-2H-benzimidazol-2-one | - |
Drosophila melanogaster |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.4.3.5 | Drosophila melanogaster | Q9VHZ5 | - |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.4.3.5 | pyridoxamine 5'-phosphate + H2O + O2 | - |
Drosophila melanogaster | pyridoxal 5'-phosphate + NH3 + H2O2 | - |
? | |
1.4.3.5 | pyridoxine 5'-phosphate + O2 | - |
Drosophila melanogaster | pyridoxal 5'-phosphate + H2O2 | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.4.3.5 | pyridoxine/pyridoxamine 5'-phosphate oxidase | - |
Drosophila melanogaster |
1.4.3.5 | sgll | - |
Drosophila melanogaster |
1.4.3.5 | Sgll/PNPO | - |
Drosophila melanogaster |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
1.4.3.5 | 0.003 | - |
pH and temperature not specified in the publication | Drosophila melanogaster | 5-[(3,4-dichlorophenyl)methoxy]-1H-indole-2,3-dione | |
1.4.3.5 | 0.046 | - |
pH and temperature not specified in the publication | Drosophila melanogaster | 5-[(3-chlorophenyl)methoxy]-1H-indole-2,3-dione | |
1.4.3.5 | 0.073 | - |
pH and temperature not specified in the publication | Drosophila melanogaster | 5-[(4-fluorophenyl)methoxy]-1H-indole-2,3-dione | |
1.4.3.5 | 0.102 | - |
pH and temperature not specified in the publication | Drosophila melanogaster | 5-[2-(4-fluorophenyl)ethoxy]-1H-indole-2,3-dione | |
1.4.3.5 | 7.68 | - |
pH and temperature not specified in the publication | Drosophila melanogaster | 6-[(3,4-dichlorophenyl)methoxy]-1-methyl-1,3-dihydro-2H-benzimidazol-2-one | |
1.4.3.5 | 17.17 | - |
pH and temperature not specified in the publication | Drosophila melanogaster | 5-[(3,4-dichlorophenyl)methoxy]-1,3-dihydro-2H-indol-2-one | |
1.4.3.5 | 24.94 | - |
pH and temperature not specified in the publication | Drosophila melanogaster | 5-[(4-fluorophenyl)methoxy]-1,3-dihydro-2H-indol-2-one | |
1.4.3.5 | 34.3 | - |
pH and temperature not specified in the publication | Drosophila melanogaster | 6-[(3-chlorophenyl)methoxy]-1-methyl-1,3-dihydro-2H-benzimidazol-2-one | |
1.4.3.5 | 56.4 | - |
pH and temperature not specified in the publication | Drosophila melanogaster | 6-[(4-chlorophenyl)methoxy]-1-methyl-1,3-dihydro-2H-benzimidazol-2-one | |
1.4.3.5 | 59.63 | - |
pH and temperature not specified in the publication | Drosophila melanogaster | 1-methyl-6-(3-phenylpropoxy)-1,3-dihydro-2H-benzimidazol-2-one | |
1.4.3.5 | 66.72 | - |
pH and temperature not specified in the publication | Drosophila melanogaster | 1-(propan-2-yl)-6-[2-[4-(propan-2-yl)phenoxy]ethoxy]-1,3-dihydro-2H-benzimidazol-2-one | |
1.4.3.5 | 116.8 | - |
pH and temperature not specified in the publication | Drosophila melanogaster | 5-[(3,4-dichlorophenyl)methoxy]-1H-indole-2,3-dione | |
1.4.3.5 | 132.4 | - |
pH and temperature not specified in the publication | Drosophila melanogaster | 5-[(3,4-dichlorophenyl)methoxy]-3,3-dimethyl-1,3-dihydro-2H-indol-2-one | |
1.4.3.5 | 184.1 | - |
pH and temperature not specified in the publication | Drosophila melanogaster | 1-ethyl-6-[[4-(trifluoromethyl)phenyl]methoxy]-1,3-dihydro-2H-benzimidazol-2-one | |
1.4.3.5 | 190.1 | - |
pH and temperature not specified in the publication | Drosophila melanogaster | 5-[2-(4-fluorophenyl)ethoxy]-1,3-dihydro-2H-indol-2-one | |
1.4.3.5 | 190.5 | - |
pH and temperature not specified in the publication | Drosophila melanogaster | 1-ethyl-6-[2-(3-fluorophenoxy)ethoxy]-1,3-dihydro-2H-benzimidazol-2-one | |
1.4.3.5 | 234.6 | - |
pH and temperature not specified in the publication | Drosophila melanogaster | 5-[(4-fluorophenyl)methoxy]-1H-indole-2,3-dione | |
1.4.3.5 | 277.6 | - |
pH and temperature not specified in the publication | Drosophila melanogaster | 1-ethyl-6-[2-[4-(propan-2-yl)phenoxy]ethoxy]-1,3-dihydro-2H-benzimidazol-2-one | |
1.4.3.5 | 279 | - |
pH and temperature not specified in the publication | Drosophila melanogaster | 5-[(3-chlorophenyl)methoxy]-3,3-dimethyl-1,3-dihydro-2H-indol-2-one | |
1.4.3.5 | 310.9 | - |
pH and temperature not specified in the publication | Drosophila melanogaster | 5-[(3-chlorophenyl)methoxy]-1H-indole-2,3-dione | |
1.4.3.5 | 396.6 | - |
pH and temperature not specified in the publication | Drosophila melanogaster | 5-[(3-fluorophenyl)methoxy]-3-(propan-2-yl)-1,3-dihydro-2H-indol-2-one |
EC Number | General Information | Comment | Organism |
---|---|---|---|
1.4.3.5 | metabolism | the enzyme is important for DNA integrity and glucose homeostasis maintenance in Drosophila | Drosophila melanogaster |