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Literature summary extracted from

  • Campbell, I.; Olmos, J.J.; Xu, W.; Kahanda, D.; Atkinson, J.; Sparks, O.; Miller, M.; Phillips, G.J.; Bennett, G.; Silberg, J.
    Prochlorococcus phage ferredoxin structural characterization and electron transfer to cyanobacterial sulfite reductases (2020), J. Biol. Chem., 295, 10610-10623 .
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.8.7.1 hydrogen sulfide + 6 oxidized ferredoxin [iron-sulfur] cluster + 3 H2O Prochlorococcus marinus
-
 sulfite + 6 reduced ferredoxin [iron-sulfur] cluster + 6 H+
-
 ?
1.8.7.1 hydrogen sulfide + 6 oxidized ferredoxin [iron-sulfur] cluster + 3 H2O Prochlorococcus marinus MIT 9211
-
 sulfite + 6 reduced ferredoxin [iron-sulfur] cluster + 6 H+
-
 ?
1.8.7.1 hydrogen sulfide + 6 oxidized ferredoxin [iron-sulfur] cluster + 3 H2O Prochlorococcus marinus NATL1A
-
 sulfite + 6 reduced ferredoxin [iron-sulfur] cluster + 6 H+
-
 ?
1.8.7.1 hydrogen sulfide + 6 oxidized ferredoxin [iron-sulfur] cluster + 3 H2O Prochlorococcus marinus NATL2A
-
 sulfite + 6 reduced ferredoxin [iron-sulfur] cluster + 6 H+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.8.7.1 Prochlorococcus marinus A2C1J2
-
-
1.8.7.1 Prochlorococcus marinus A9BAS4
-
-
1.8.7.1 Prochlorococcus marinus Q46LH4
-
-
1.8.7.1 Prochlorococcus marinus MIT 9211 A9BAS4
-
-
1.8.7.1 Prochlorococcus marinus NATL1A A2C1J2
-
-
1.8.7.1 Prochlorococcus marinus NATL2A Q46LH4
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.8.7.1 hydrogen sulfide + 6 oxidized ferredoxin [iron-sulfur] cluster + 3 H2O
-
 Prochlorococcus marinus sulfite + 6 reduced ferredoxin [iron-sulfur] cluster + 6 H+
-
 ?
1.8.7.1 hydrogen sulfide + 6 oxidized ferredoxin [iron-sulfur] cluster + 3 H2O
-
 Prochlorococcus marinus MIT 9211 sulfite + 6 reduced ferredoxin [iron-sulfur] cluster + 6 H+
-
 ?
1.8.7.1 hydrogen sulfide + 6 oxidized ferredoxin [iron-sulfur] cluster + 3 H2O
-
 Prochlorococcus marinus NATL1A sulfite + 6 reduced ferredoxin [iron-sulfur] cluster + 6 H+
-
 ?
1.8.7.1 hydrogen sulfide + 6 oxidized ferredoxin [iron-sulfur] cluster + 3 H2O
-
 Prochlorococcus marinus NATL2A sulfite + 6 reduced ferredoxin [iron-sulfur] cluster + 6 H+
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.8.7.1 SIR
-
 Prochlorococcus marinus
1.8.7.1 sulfite reductase
-
 Prochlorococcus marinus

Cofactor

EC Number Cofactor Comment Organism Structure
1.8.7.1 Ferredoxin the enzyme can use its endogenous ferredoxin as well as the ferredoxin pssm2-Fd from its parasite myovirus P-SSM2. pssm2-Fd contains sequence features of host Fds, structure of the pssm2-Fd and structure comparisons, overview. Prochlorococcus marinus ferredoxin contains [4Fe-4S] centers, the myoviral ferredoxin contains [2Fe-2S] centers Prochlorococcus marinus
1.8.7.1 additional information when expressed in an Escherichia coli strain deficient in sulfite assimilation, pssm2-Fd complements bacterial growth when coexpressed with a Prochlorococcus marinus sulfite reductase, revealing that pssm2-Fd can transfer electrons to a host protein involved in nutrient assimilation. The high levels of structural similarity with cyanobacterial Fds and reactivity with a host sulfite reductase suggest that phage Fds evolved to transfer electrons to cyanobacterially encoded oxidoreductases. The phage Fds all localize to cluster VI, in close association with cyanobacterial Fds. Among the Fds in cluster VI, interactions with a range of oxidoreductases have been documented. Evaluation of the surface charge distribution of several different Fd and SIR structures Prochlorococcus marinus

General Information

EC Number General Information Comment Organism
1.8.7.1 physiological function the life cycle of Prochlorococcus marinus is influenced by viruses. Cyanophages that infect it have evolved genomes with as many as 327 open reading frames (ORFs). Viruses from three clades infect Prochlorococcus marinus, including T4-like myoviruses, T7-like podoviruses, and, less commonly, members of Siphoviridae. In some ecosystems, as many as 50% of cyanobacteria may be infected at any point in time. The sulfite reductase from Prochlorococcus marinus can utilize, besides its endogenous ferredoxin, also the phage ferredoxin, pssm2-Fd, from its parasite myovirus P-SSM2 Prochlorococcus marinus