Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Chen, T.; Chen, J.; Tang, Y.; Zhou, J.; Guo, Y.; Chang, W.
    Pathway from N-alkylglycine to alkylisonitrile catalyzed by iron(II) and 2-oxoglutarate-dependent oxygenases (2020), Angew. Chem. Int. Ed.Engl., 59, 7367-7371 .
    View publication on PubMed

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
1.14.11.78 structures of iron-loaded ScoE in complex with its substrate and the intermediate show that -NC bond formation involves two cycles of Fe/2OG enzyme catalysis Streptomyces coeruleorubidus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
1.14.11.78 Iron in the crystal structure, the octahedron geometry of iron is bound by a 2-His-1-Asp facial triad H132, D134, and H295 Streptomyces coeruleorubidus

Organism

EC Number Organism UniProt Comment Textmining
1.14.11.78 Streptomyces avermitilis
-
-
-
1.14.11.78 Streptomyces coeruleorubidus A0A3B6UEU3
-
-
1.14.11.78 Streptomyces thioluteus
-
-
-

Synonyms

EC Number Synonyms Comment Organism
1.14.11.78 Sav607
-
 Streptomyces avermitilis
1.14.11.78 scoE
-
 Streptomyces coeruleorubidus
1.14.11.78 SfaA
-
 Streptomyces thioluteus

General Information

EC Number General Information Comment Organism
1.14.11.78 metabolism -NC bond formation involves two cycles of Fe/2OG enzyme catalysis, each consuming an oxygen molecule and a 2-oxoglutarate molecule. The reaction starts with an Fe(IV)-oxo catalyzed hydroxylation Streptomyces avermitilis
1.14.11.78 metabolism -NC bond formation involves two cycles of Fe/2OG enzyme catalysis, each consuming an oxygen molecule and a 2-oxoglutarate molecule. The reaction starts with an Fe(IV)-oxo catalyzed hydroxylation Streptomyces coeruleorubidus
1.14.11.78 metabolism -NC bond formation involves two cycles of Fe/2OG enzyme catalysis, each consuming an oxygen molecule and a 2-oxoglutarate molecule. The reaction starts with an Fe(IV)-oxo catalyzed hydroxylation Streptomyces thioluteus